CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041196
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 General transcription factor II-I 
Protein Synonyms/Alias
  
Gene Name
 Gtf2i 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
219SGSCGPIKVKTEPTEubiquitination[1]
268VREFNFEKWNARITDacetylation[2]
365REDLQLDKPASGVKEacetylation[2, 3]
371DKPASGVKEEWYARIacetylation[3]
383ARITKLRKMVDQLFCacetylation[3]
391MVDQLFCKKFAEALGacetylation[3]
392VDQLFCKKFAEALGSacetylation[3]
441YGIPRLEKIIQVGNRacetylation[3]
476PRTNTPVKEDWNVRIacetylation[3]
630NGSNVPFKPRGREFSacetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 913 AA 
Protein Sequence
MAQVVMSALP AEDEESSESR MVVTFLMSAL ESMCKELAKS KAEVACIAVY ETDVFVVGTE 60
RGRAFVNTRK DFQKDFVKYC VEEEEKAAEM HKMKSTTQAN RMSVDAVEIE TLRKTVEDYF 120
CFCYGKALGK STVVPVPYEK MLRDQSAVVV QGLPEGVAFK HPEHYDLATL KWILENKAGI 180
SFIIKRPFLE PKKHLGGRVL AAEAERSMLS PSGSCGPIKV KTEPTEDSDD DYSPPTKRLK 240
STEPPPPPPV PEPANAGKRK VREFNFEKWN ARITDLRKQV EELFERKYAQ AIKAKGPVTI 300
PYPLFQSHVE DLYVEGLPEG IPFRRPSTYG IPRLERILLA KERIRFVIKK HELLNSTRED 360
LQLDKPASGV KEEWYARITK LRKMVDQLFC KKFAEALGST EAKAVPYQKF EAHPNDLYVE 420
GLPENIPFRS PSWYGIPRLE KIIQVGNRIK FVIKRPELLT HSTTEVTQPR TNTPVKEDWN 480
VRITKLRKQV EEIFNLKFAQ ALGLTEAVKV PYPVFESNPE FLYVEGLPEG IPFRSPTWFG 540
IPRLERIVRG SNKIKFVVKK PELVVSYLPP GMASKINTKA LQSPKRPRSP GSNSKVPEIE 600
VTVEGPNNSS PQTSAVRTPT QTNGSNVPFK PRGREFSFEA WNAKITDLKQ KVENLFNEKC 660
GEALGLKQAV KVPFALFESF PEDFYVEGLP EGVPFRRPST FGIPRLEKIL RNKAKIKFII 720
KKPEMFETAI KESTSSKSPP RKINSSPNVN TTASGVEDLN IIQVTIPDDD NERLSKVEKA 780
RQLREQVNDL FSRKFGEAIG MGFPVKVPYR KITINPGCVV VDGMPPGVSF KAPSYLEISS 840
MRRILDSAEF IKFTVIRPFP GLVINNQLVD QNESEGPVIQ ESAEASQLEV PVTEEIKETD 900
GSSQIKQEPD PTW 913 
Gene Ontology
 GO:0042995; C:cell projection; IDA:MGI.
 GO:0043025; C:neuronal cell body; IDA:MGI.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0051019; F:mitogen-activated protein kinase binding; IDA:MGI.
 GO:0009790; P:embryo development; IMP:MGI. 
Interpro
 IPR004212; GTF2I.
 IPR016659; TF_II-I. 
Pfam
 PF02946; GTF2I 
SMART
  
PROSITE
 PS51139; GTF2I 
PRINTS