CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043412
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Transcription factor 25 
Protein Synonyms/Alias
  
Gene Name
 TCF25 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
54LNPDTELKRYFGARAubiquitination[1, 2, 3]
93STWPRYSKPGLSMRLubiquitination[1, 2, 3, 4]
105MRLLESKKGLSFFAFubiquitination[2]
218KQMSFLEKRGCPRTAubiquitination[1]
407EACENRRKVLYQRAPubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 570 AA 
Protein Sequence
XGEASENGLE DIDRILERIE DSTGLNRPGP APLSSRKHVL YVEHRHLNPD TELKRYFGAR 60
AILGEQRPRQ RQRVYPKCTW LTTPKSTWPR YSKPGLSMRL LESKKGLSFF AFEHSEEYQQ 120
AQHKFLVAVE SMEPNNIVVL LQTSPYHVDS LLQLSDACRF QEDQEMARDL VERALYSMEC 180
AFHPLFSLTS GACRLDYRRP ENRSFYLALY KQMSFLEKRG CPRTALEYCK LILSLEPDED 240
PLCMLLLIDH LALRARNYEY LIRLFQEWEA HRNLSQLPNF AFSVPLAYFL LSQQTDLPEC 300
EQSSARQKAS LLIQQALTMF PGVLLPLLES CSVRPDASVS SHRFFGPNAE ISQPPALSQL 360
VNLYLGRSHF LWKEPATMSW LEENVHEVLQ AVDAGDPAVE ACENRRKVLY QRAPRNIHRH 420
VILSEIKEAV AALPPDVTTQ SVMGFDPLPP SDTIYSYVRP ERKGEEERNS VIWGSQLCVC 480
RPRSFPSPPN VQALACRPLW QAKSYQPWKH HCSLLPVTVA KLYHGGGEAR GRSGWGSEPQ 540
PGPEQADAGC ARHDGQLPPQ RPGGAARGRR 570 
Gene Ontology
  
Interpro
 IPR006994; TCF25.
 IPR011990; TPR-like_helical. 
Pfam
 PF04910; Tcf25 
SMART
  
PROSITE
  
PRINTS