CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042553
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Regulator of G-protein-signaling 14 
Protein Synonyms/Alias
  
Gene Name
 RGS14 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
46DSYARFVKSPLYRECubiquitination[1]
157SKSESHRKSLGSTEGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 437 AA 
Protein Sequence
XSPVNIDRQA WLGEEVLAEP RPDMFRAQQL QIFNLMKFDS YARFVKSPLY RECLLAEAEG 60
RPLREPGSSR LGSPDATRKK PKLKPGKSLP LGVEELGQLP PVEGPGGRPL RKSFRRELGG 120
TANAALRRES QGSLNSSASL DLGFLAFVSS KSESHRKSLG STEGESESRP GKYCCVYLPD 180
GTASLALARP GLTIRDMLAG ICEKRGLSLP DIKVYLVGNE QKALVLDQDC TVLADQEVRL 240
ENRITFELEL TALERVVRIS AKPTKRLQEA LQPILEKHGL SPLEVVLHRP GEKQPLDLGK 300
LVSSVAAQRL VLDTLPGVKI SKARDKSPCR SQGCPPRTQD KATHPPPASP SSLVKVPSSA 360
TGKRQTCDIE GLVELLNRVQ SSGAHDQRGL LRKEDLVLPE FLQLPAQGPS SEETPPQTKS 420
AAQPIGGSLN STTDSAL 437 
Gene Ontology
 GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0030695; F:GTPase regulator activity; IEA:InterPro.
 GO:0005057; F:receptor signaling protein activity; IEA:InterPro.
 GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro. 
Interpro
 IPR003109; GoLoco_motif.
 IPR003116; Raf-like_ras-bd.
 IPR000342; Regulat_G_prot_signal.
 IPR016137; Regulat_G_prot_signal_superfam. 
Pfam
 PF02188; GoLoco
 PF02196; RBD
 PF00615; RGS 
SMART
 SM00390; GoLoco
 SM00455; RBD 
PROSITE
 PS50877; GOLOCO
 PS50898; RBD
 PS50132; RGS 
PRINTS