CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041220
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 T-complex protein 1 subunit delta 
Protein Synonyms/Alias
  
Gene Name
 Cct4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
55IRTSLGPKGMDKMIQacetylation[1]
55IRTSLGPKGMDKMIQsuccinylation[1]
55IRTSLGPKGMDKMIQubiquitination[2]
65DKMIQDGKGDVTITNubiquitination[2]
79NDGATILKQMQVLHPubiquitination[2]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Chaperone; Complete proteome; Cytoplasm; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 120 AA 
Protein Sequence
MPENVASRSG APTAGPGSRG KSAYQDRDKP AQIRFSNISA AKAVADAIRT SLGPKGMDKM 60
IQDGKGDVTI TNDGATILKQ MQVLHPAARM VYIQPSFPSH SRKLWKRVLK SLLTCLDLCN 120 
Gene Ontology
 GO:0044297; C:cell body; IDA:MGI.
 GO:0005832; C:chaperonin-containing T-complex; IDA:MGI.
 GO:0002199; C:zona pellucida receptor complex; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0007339; P:binding of sperm to zona pellucida; IDA:MGI.
 GO:0006457; P:protein folding; IEA:InterPro. 
Interpro
 IPR012717; Chap_CCT_delta.
 IPR017998; Chaperone_TCP-1.
 IPR002194; Chaperonin_TCP-1_CS.
 IPR002423; Cpn60/TCP-1.
 IPR027413; GROEL-like_equatorial. 
Pfam
 PF00118; Cpn60_TCP1 
SMART
  
PROSITE
 PS00750; TCP1_1
 PS00751; TCP1_2 
PRINTS
 PR00304; TCOMPLEXTCP1.