UniProt Accession

 K6PF_MYCPN; P75476 

Genbank Protein ID

 U00089 

Genbank Nucleotide ID

 AAB96182.1 

Protein Name

 6-phosphofructokinase 

Protein Synonyms/Alias

 Phosphofructokinase; Phosphohexokinase 

Gene Name

 pfkA 

Gene Synonyms/Alias

 pfk; MPN_302; MP534 

Created Date

 July 27, 2013 

Organism

 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 

NCBI Taxa ID

 272634 

Lysine Modification

Position	Peptide	Type	References
82	SKRFVEFKELKVREQ	acetylation	[1]
204	PSNKMDLKQLESAVK	acetylation	[1]

Reference

 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 

Functional Description

  

Sequence Annotation

 NP_BIND 26 30 ATP (By similarity).
 NP_BIND 159 163 ATP (By similarity).
 NP_BIND 176 192 ATP (By similarity).
 ACT_SITE 132 132 Proton acceptor (By similarity).
 BINDING 167 167 Substrate (By similarity).
 BINDING 258 258 Substrate (By similarity).
 BINDING 261 261 Substrate (By similarity).  

Keyword

 Allosteric enzyme; ATP-binding; Complete proteome; Cytoplasm; Glycolysis; Kinase; Nucleotide-binding; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 328 AA 

Protein Sequence

Gene Ontology

 GO:0005945; C:6-phosphofructokinase complex; IEA:InterPro.
 GO:0003872; F:6-phosphofructokinase activity; IEA:HAMAP.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
 GO:0006096; P:glycolysis; IEA:HAMAP. 

Interpro

 IPR012003; ATP_PFK_prok.
 IPR022953; Phosphofructokinase.
 IPR000023; Phosphofructokinase_dom. 

Pfam

 PF00365; PFK 

SMART

  

PROSITE

 PS00433; PHOSPHOFRUCTOKINASE 

PRINTS

 PR00476; PHFRCTKINASE.