Tag | Content |
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CPLM ID | CPLM-003567 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Transcriptional regulatory protein GlrR |
Protein Synonyms/Alias | |
Gene Name | glrR |
Gene Synonyms/Alias | yfhA; b2554; JW2538 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
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110 | FLTKPVDKDALYQAI | acetylation | [1] | 430 | RNRTEFYKLLSRHEL | acetylation | [1] |
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Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Member of the two-component regulatory system GlrR/GlrK that up-regulates transcription of the glmY sRNA when cells enter the stationary growth phase. Regulates glmY transcription by binding to three conserved sites in the purL-glmY intergenic region. |
Sequence Annotation | DOMAIN 7 121 Response regulatory. DOMAIN 136 366 Sigma-54 factor interaction (Potential). NP_BIND 164 171 ATP (Potential). NP_BIND 227 236 ATP (Potential). DNA_BIND 414 433 H-T-H motif (Potential). MOD_RES 56 56 4-aspartylphosphate (By similarity). |
Keyword | ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Nucleotide-binding; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Two-component regulatory system. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 444 AA |
Protein Sequence | MSHKPAHLLL VDDDPGLLKL LGLRLTSEGY SVVTAESGAE GLRVLNREKV DLVISDLRMD 60 EMDGMQLFAE IQKVQPGMPV IILTAHGSIP DAVAATQQGV FSFLTKPVDK DALYQAIDDA 120 LEQSAPATDE RWREAIVTRS PLMLRLLEQA RLVAQSDVSV LINGQSGTGK EIFAQAIHNA 180 SPRNSKPFIA INCGALPEQL LESELFGHAR GAFTGAVSNR EGLFQAAEGG TLFLDEIGDM 240 PAPLQVKLLR VLQERKVRPL GSNRDIDINV RIISATHRDL PKAMARGEFR EDLYYRLNVV 300 SLKIPALAER TEDIPLLANH LLRQAAERHK PFVRAFSTDA MKRLMTASWP GNVRQLVNVI 360 EQCVALTSSP VISDALVEQA LEGENTALPT FVEARNQFEL NYLRKLLQIT KGNVTHAARM 420 AGRNRTEFYK LLSRHELDAN DFKE 444 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. GO:0000156; F:phosphorelay response regulator activity; IMP:EcoCyc. GO:0006355; P:regulation of transcription, DNA-dependent; IEP:EcoCyc. GO:0006351; P:transcription, DNA-dependent; IDA:EcoCyc. |
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PRINTS | |