CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-033750
UniProt Accession
C9K0R9_HUMAN
;
C9K0R9
Genbank Protein ID
AC010655
Genbank Nucleotide ID
Protein Name
Inosine-5'-monophosphate dehydrogenase 1
Protein Synonyms/Alias
Gene Name
IMPDH1
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Homo sapiens (Human)
NCBI Taxa ID
9606
Lysine Modification
Position
Peptide
Type
References
150
VGDVLEA
K
MRHGFSG
ubiquitination
[1]
Reference
[1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
Mol Cell. 2011 Oct 21;44(2):325-40. [
PMID: 21906983
]
Functional Description
Sequence Annotation
Keyword
Complete proteome; Reference proteome.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
289 AA
Protein Sequence
MEGPLTPPPL QGGGAAAVPE PGARQHPGHE TAAQRYSARL LQAGYEPESD FLILPGFIDF 60
IADEVDLTSA LTRKITLKTP LISSPMDTVT EADMAIAMAL MGGIGFIHHN CTPEFQANEV 120
RKVKKFEQGF ITDPVVLSPS HTVGDVLEAK MRHGFSGIPI TETGTMGSKL VGIVTSRDID 180
FLAEKDHTTL LSEVMTPRIE LVVAPAGVTL KEANEILQRS KKGKLPIVND CDELVAIIAR 240
TDLKKNRDYP LASKDSQKQL LCGAAVGTRE DDKYRLDLLT QAGVDVIVL 289
Gene Ontology
GO:0003938
; F:IMP dehydrogenase activity; IEA:InterPro.
GO:0006164
; P:purine nucleotide biosynthetic process; IEA:InterPro.
Interpro
IPR013785
; Aldolase_TIM.
IPR000644
; Cysta_beta_synth_core.
IPR005990
; IMP_DH.
IPR001093
; IMP_DH_GMPRt.
Pfam
PF00571
; CBS
PF00478
; IMPDH
SMART
SM00116
; CBS
PROSITE
PS51371
; CBS
PRINTS