CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007071
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 40S ribosomal protein SA 
Protein Synonyms/Alias
 K14; Laminin receptor homolog; Protein stubarista 
Gene Name
 sta 
Gene Synonyms/Alias
 CG14792 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
132IGQRAVLKFAKYTDTacetylation[1]
135RAVLKFAKYTDTTPIacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
 Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Required during oogenesis and imaginal development. 
Sequence Annotation
  
Keyword
 3D-structure; Alternative splicing; Complete proteome; Cytoplasm; Developmental protein; Nucleus; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 313 AA 
Protein Sequence
MCRRLWRQAR HRRKVARGAP SLRLCPLTIC LSRSQVRNSF HVNMSGGLDI LSLKEDDITK 60
MLVATTHLGS ENVNFQMEQY VYKRRADGVN ILNLGKTWEK LQLAARAIVA IDNPSDIFVI 120
SSRPIGQRAV LKFAKYTDTT PIAGRFTPGA FTNQIQPAFR EPRLLVVTDP NTDHQPIMEA 180
SYVNIPVIAF TNTDSPLRYI DIAIPCNNKS AHSIGLMWWL LAREVLRLRG TISRSVEWPV 240
VVDLFFYRDP EEAEKEEAAA KELLPPPKIE EAVDHPVEET TNWADEVAAE TVGGVEDWNE 300
DTVKTSWGSD GQF 313 
Gene Ontology
 GO:0030686; C:90S preribosome; IBA:RefGenome.
 GO:0022627; C:cytosolic small ribosomal subunit; IBA:RefGenome.
 GO:0005875; C:microtubule associated complex; IDA:FlyBase.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0043022; F:ribosome binding; IPI:UniProtKB.
 GO:0003735; F:structural constituent of ribosome; IDA:FlyBase.
 GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:RefGenome.
 GO:0000461; P:endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:RefGenome.
 GO:0000022; P:mitotic spindle elongation; IMP:FlyBase.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
 GO:0000028; P:ribosomal small subunit assembly; IBA:RefGenome.
 GO:0006407; P:rRNA export from nucleus; IBA:RefGenome.
 GO:0006412; P:translation; IBA:RefGenome. 
Interpro
 IPR001865; Ribosomal_S2.
 IPR018130; Ribosomal_S2_CS.
 IPR027498; Ribosomal_S2_euk.
 IPR005707; Ribosomal_S2_euk/arc.
 IPR023591; Ribosomal_S2_flav_dom. 
Pfam
 PF00318; Ribosomal_S2 
SMART
  
PROSITE
 PS00962; RIBOSOMAL_S2_1
 PS00963; RIBOSOMAL_S2_2 
PRINTS
 PR00395; RIBOSOMALS2.