| Tag | Content |
|---|
| CPLM ID | CPLM-016927 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Translation initiation factor IF-2 |
Protein Synonyms/Alias | |
Gene Name | infB |
Gene Synonyms/Alias | LA_0943 |
Created Date | July 27, 2013 |
Organism | Leptospira interrogans serogroup Icterohaemorrhagiae serovar La |
NCBI Taxa ID | 189518 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 655 | ENMNEFIKQGALKEL | methylation | [1] |
|
Reference | [1] High-coverage proteome analysis reveals the first insight of protein modification systems in the pathogenic spirochete Leptospira interrogans. Cao XJ, Dai J, Xu H, Nie S, Chang X, Hu BY, Sheng QH, Wang LS, Ning ZB, Li YX, Guo XK, Zhao GP, Zeng R. Cell Res. 2010 Feb;20(2):197-210. [ PMID: 19918266] |
Functional Description | One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity). |
Sequence Annotation | NP_BIND 367 374 GTP (By similarity).
NP_BIND 413 417 GTP (By similarity).
NP_BIND 467 470 GTP (By similarity).
REGION 361 509 G-domain. |
Keyword | Complete proteome; Cytoplasm; GTP-binding; Initiation factor; Nucleotide-binding; Protein biosynthesis; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 863 AA |
Protein Sequence | MEDKNKTIKE TLQGSADAGK RKKLIIKKKG DDPSTPSPAA SPKKETVAES APSSKPPVMP 60
LPLPGDSGQS PIVRPAPSSH SPAKREESPG KQDAGRPPRD KDTRQGGGSS YPPSRSPFQK 120
EDSNIIVSRP IQRTGPSRPN SGGGYQGNRG PGQGGGGYQG NRGPGQGGGG YQGNRGPGPG 180
QGGGGYQGNR GPGQGGGGYQ GNRGPRSGGT GTRPMPITSA EVELSQSRGS SVTSKKKGHD 240
KEKSTSDRDF SGAENTKFFK QKFKKTKVVG VSGVSVPKEI TLLENVQVGE LAKKMNLKPG 300
DVIGKLMKMG MMVTINNIID AETAALLADE YGCKVKVVSL YEETIIEEEK DNQEDYINRP 360
PVVTIMGHVD HGKTKLLDTI RRSSVIDTES GGITQHIGAY QVRTARGLIT FLDTPGHEAF 420
TSMRARGAKV TDIVVLVVAA DDGVMPQTLE AISHAKAAEV PILVAINKID LPAANPEKIM 480
QELANHGLQS EEWGGETMYA KISARENIGI DKLLEMILLQ AEVMDLKANP KRRAKGTIIE 540
AKLDPGRGSV ATVLIQNGTL RVGDPFVAGV FSGRVRAMYN DLGQLIQEAG PAFPAQVTGI 600
DGVPDAGAPF DAMADEKEAR NISQHRIEFE RIGNAGAATG TSSKVTLENM NEFIKQGALK 660
ELKVIIKADV RGSAEAIKES LEKLSTPEVK LNVIQSGAGA IVDMDVMLAS ASNALIIGFH 720
VRANPKTIAL AEKEGVQIKY YNIIYQVVDE IKLAMEGLLE PEKIEEVIGT AEIREIFKVS 780
KIGNIAGCMV LSGKIQKSAN IRVIGDGVTK FEGKLKSLKR VKDDVNDVVA GFECGIQVDG 840
YNDFKVGDTI EAYNVTVIKR KLE 863 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |