UniProt Accession

 GBRAP_MOUSE; Q9DCD6; B1AR49; Q9QUI7 

Genbank Protein ID

 AF161587; AK002879; AK011731; AL596185; BC002126; BC024621; BC030350 

Genbank Nucleotide ID

 AAD47642.1; BAB22426.1; BAB27806.1; CAI35162.1; AAH02126.1; AAH24621.1; AAH30350.1 

Protein Name

 Gamma-aminobutyric acid receptor-associated protein 

Protein Synonyms/Alias

 GABA(A) receptor-associated protein 

Gene Name

 Gabarap 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
13	KEEHPFEKRRSEGEK	ubiquitination	[1]
24	EGEKIRKKYPDRVPV	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Ubiquitin-like modifier that play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity). 

Sequence Annotation

 REGION 1 22 Interaction with beta-tubulin.
 REGION 36 117 Interaction with GPHN.
 REGION 36 68 Interaction with GABRG2 (Potential).
 LIPID 116 116 Phosphatidylethanolamine amidated  

Keyword

 Apoptosis; Autophagy; Complete proteome; Cytoplasm; Cytoplasmic vesicle; Cytoskeleton; Golgi apparatus; Lipoprotein; Membrane; Microtubule; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 117 AA 

Protein Sequence

Gene Ontology

 GO:0015629; C:actin cytoskeleton; IDA:MGI.
 GO:0005776; C:autophagic vacuole; ISS:UniProtKB.
 GO:0000421; C:autophagic vacuole membrane; IEA:Compara.
 GO:0044297; C:cell body; IEA:Compara.
 GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
 GO:0005794; C:Golgi apparatus; IDA:MGI.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0005764; C:lysosome; IDA:MGI.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005875; C:microtubule associated complex; IDA:MGI.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
 GO:0005886; C:plasma membrane; IDA:MGI.
 GO:0005790; C:smooth endoplasmic reticulum; IDA:MGI.
 GO:0008017; F:microtubule binding; IDA:MGI.
 GO:0006914; P:autophagy; IEA:UniProtKB-KW.
 GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; ISS:UniProtKB.
 GO:0000226; P:microtubule cytoskeleton organization; IDA:MGI.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 

Interpro

 IPR004241; Atg8_ubiquitin-like. 

Pfam

 PF02991; Atg8 

SMART

  

PROSITE

  

PRINTS