CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017662
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tetratricopeptide repeat protein 16 
Protein Synonyms/Alias
 TPR repeat protein 16 
Gene Name
 TTC16 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
246QARMLLQKMVAQAQQubiquitination[1]
266GILAVQGKLQHALQRubiquitination[1]
365LRDEQQEKGLYINRGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
 REPEAT 61 94 TPR 1.
 REPEAT 96 128 TPR 2.
 REPEAT 136 169 TPR 3.
 REPEAT 251 284 TPR 4.
 REPEAT 285 318 TPR 5.
 REPEAT 331 364 TPR 6.
 REPEAT 365 398 TPR 7.
 REPEAT 406 439 TPR 8.  
Keyword
 Complete proteome; Polymorphism; Reference proteome; Repeat; TPR repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 873 AA 
Protein Sequence
MTDSDEDALK VDQGPSRDIP KPWVIPAPKG ILQHIFGTSH VFQSICDVKP KVTGLTVPLK 60
VREYYSRGQQ CLEQADWETA VLLFSRALHL DPQLVDFYAL RAEAYLQLCD FSSAAQNLRR 120
AYSLQQDNCK HLERLTFVLY LQGQCLFEQC AFLDALNVFS HAAELQPEKP CFRYRCMACL 180
LALKQHQACL TLITNELKQD TTNADVYIFR ARLYNFLQKP HLCYRDLHSA LLLNPKHPQA 240
RMLLQKMVAQ AQQARQDAGI LAVQGKLQHA LQRINRAIEN NPLDPSLFLF RGTMYRRLQE 300
FDGAVEDFLK VLDMVTEDQE DMVRQAQRQL LLTYNDFAVH CYRQGAYQEG VLLLNKALRD 360
EQQEKGLYIN RGDCFFQLGN LAFAEADYQQ ALALSPQDEG ANTRMGLLQE KMGFCEQRRK 420
QFQKAENHFS TAIRHNPQKA QYYLYRAKSR QLLQNIFGAR QDVATVLLLN PKQPKLSLLM 480
TNLFPGMSVE EVLSTQIAHL ARLQLEQMVE GSLQAGSPQG IVGMLKRHEL ERQKALALQH 540
SWKQGEPLIA TSEELKATPE IPQVKPGSSE GEAEAPEEEE EKEKEKKEEK KSELIPSKVA 600
SLSDSYLDQT SSASSMSFRT TGTSETEMSA ICQEYRSTSA TAVTFSDSSL LKTQSSDSGN 660
NREALSHGPR KIKATQGQRQ SLSKTEPTQS QRRNSSKTKA TIHKRNSSKT KATQSQRRNS 720
SKTRATQGQG QSSSKTEATQ GQRQSSSEIE ATQGPRQEPS KTKTTRSPRQ RPRKVKAARG 780
RSWRPSKVDA TQGRSRGLLR SSTKTEAFYD SNWSLSKTEY AQGQGQRSSK AEGAQGKSQG 840
MSSTSSKAES TWGPSPSLSK TEVDQDLTYY EAV 873 
Gene Ontology
  
Interpro
 IPR001440; TPR-1.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF00515; TPR_1 
SMART
 SM00028; TPR 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS