CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019485
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 t-SNARE domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 TSNARE1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
125TTRAKKRKPNFCPQEacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
  
Sequence Annotation
 DOMAIN 416 478 t-SNARE coiled-coil homology.  
Keyword
 Coiled coil; Complete proteome; Membrane; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 513 AA 
Protein Sequence
MSYGSIARGG GLGSRGPFGG PSRQGCQPLE CARCWTEYGI RHFPCPSPES KLQNRCVGKD 60
GEGDLGPAGT PIVPRARKRG PGVAPEGSRM PEPTSSPTIG PRKDSAAGPH GRMAGPSTTR 120
AKKRKPNFCP QETEVLVSKV SKHHQLLFGT GLLKAEPTRR YRVWSRILQA VNALGYCRRD 180
VVDLKHKWRD LRAVVRRKLG DLRKAAHGPS PGSGKPQALA LTPVEQVVAK TFSCQALPSE 240
GFSLEPPRAT QVDPCNLQEL FQEMSANVFR INSSVTSLER SLQSLGTPSD TQELRDSLHT 300
AQQETNKTIA ASASSVKQMA ELLRSSCPQE RLQQERPQLD RLKTQLSDAI QCYGVVQKKI 360
AEKSRALLPM AQRGSKQSPQ APFAELADDE KVFNGSDNMW QGQEQALLPD ITEEDLEAIR 420
LREEAILQME SNLLDVNQII KDLASMVSEQ GEAVDSIEAS LEAASSHAEA ARQLLAGASR 480
HQLQRHKIKC CFLSAGVTAL LVIIIIIATS VRK 513 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0031201; C:SNARE complex; IBA:RefGenome.
 GO:0005484; F:SNAP receptor activity; IBA:RefGenome.
 GO:0000149; F:SNARE binding; IBA:RefGenome.
 GO:0006886; P:intracellular protein transport; IBA:RefGenome.
 GO:0016079; P:synaptic vesicle exocytosis; IBA:RefGenome. 
Interpro
 IPR010989; t-SNARE.
 IPR000727; T_SNARE_dom. 
Pfam
 PF05739; SNARE 
SMART
 SM00397; t_SNARE 
PROSITE
 PS50192; T_SNARE 
PRINTS