| Tag | Content |
|---|
| CPLM ID | CPLM-015898 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 550 |
Protein Synonyms/Alias | |
Gene Name | ZNF550 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 137 | EGLLEMQKGKVTPET | ubiquitination | [1] | | 154 | HKETHLGKVSLEGEG | ubiquitination | [1] | | 215 | CGKGFNRKWYLVRHQ | ubiquitination | [1] | | 313 | NRTHTGEKPFECKEC | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 12 83 KRAB.
ZN_FING 203 225 C2H2-type 1.
ZN_FING 231 253 C2H2-type 2.
ZN_FING 259 281 C2H2-type 3.
ZN_FING 287 309 C2H2-type 4.
ZN_FING 315 337 C2H2-type 5.
ZN_FING 343 365 C2H2-type 6.
ZN_FING 371 393 C2H2-type 7.
ZN_FING 399 421 C2H2-type 8. |
Keyword | Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 422 AA |
Protein Sequence | MAETKDAAQM LVTFKDVAVT FTREEWRQLD LAQRTLYREV MLETCGLLVS LGHRVPKPEL 60
VHLLEHGQEL WIVKRGLSHA TCAGDRAQVH TREPTTYPPV LSERAFLRGS LTLESSTSSD 120
SRLGRARDEE GLLEMQKGKV TPETDLHKET HLGKVSLEGE GLGTDDGLHS RALQEWLSAD 180
VLHECDSQQP GKDALIHAGT NPYKCKQCGK GFNRKWYLVR HQRVHTGMKP YECNACGKAF 240
SQSSTLIRHY LIHTGEKPYK CLECGKAFKR RSYLMQHHPI HTGEKPYECS QCRKAFTHRS 300
TFIRHNRTHT GEKPFECKEC EKAFSNRAHL IQHYIIHTGE KPYDCMACGK AFRCSSELIQ 360
HQRIHTGEKP YECTQCGKAF HRSTYLIQHS VIHTGEMPYK CIECGKAFKR RSHLLQHQRV 420
HT 422 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |