CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016997
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ADP-ribosylation factor-like protein 17 
Protein Synonyms/Alias
 ADP-ribosylation factor 7 variant 
Gene Name
 ARL17A; ARL17B 
Gene Synonyms/Alias
 ARL17P1; ARF1P2; ARL17A; PRO2667 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
15LFKSLLGKKKMRILIubiquitination[1]
16FKSLLGKKKMRILILubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). 
Sequence Annotation
 NP_BIND 24 31 GTP (By similarity).
 NP_BIND 67 71 GTP (By similarity).
 NP_BIND 125 128 GTP (By similarity).
 LIPID 2 2 N-myristoyl glycine (Potential).  
Keyword
 Alternative splicing; Complete proteome; ER-Golgi transport; Golgi apparatus; GTP-binding; Lipoprotein; Myristate; Nucleotide-binding; Polymorphism; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 177 AA 
Protein Sequence
MGNIFEKLFK SLLGKKKMRI LILSLDTAGK TTILYKLKLG ETVPAVPTVG FCVETVEYKN 60
NTFAVWDVGS HFKIRPLWQH FFQNTKGARS PGSTHQGSLA SGVLPIKCSH VEFGMWKGGR 120
SHPFLPHSSR CAGSGGQLDS ILPHQSPAWG PWGCKDLSSG FPSFLTSSIL WKSAVVK 177 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR024156; Small_GTPase_ARF.
 IPR006689; Small_GTPase_ARF/SAR. 
Pfam
 PF00025; Arf 
SMART
  
PROSITE
 PS51417; ARF 
PRINTS
 PR00328; SAR1GTPBP.