| Tag | Content |
|---|
| CPLM ID | CPLM-016047 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ras association domain-containing protein 6 |
Protein Synonyms/Alias | |
Gene Name | Rassf6 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 95 | TPETFSSKGRMTRWG | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Involved in the induction of apoptosis. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B. |
Sequence Annotation | DOMAIN 202 290 Ras-associating.
DOMAIN 297 344 SARAH. |
Keyword | Alternative splicing; Apoptosis; Complete proteome; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 353 AA |
Protein Sequence | MTAMDHQFPS WIVVNESTSI SREQLNYLLE TYNVFYENQK NLHILYGQTE DGQLIVEGML 60
DIFWGVKRPI QLKIQDEKQI SSFDLLNTPE TFSSKGRMTR WGEFDDLYRI SELDRTHVLA 120
SEARHSPEDY LSYHSTLTPY ADEEPESPLL YRTMSEAESP LLYRTMSEAA LVRKRMRAPE 180
MYRKDRMGVL SNHRASINGH VYDHETSIFT PTFGSETKVR ANSIMRTEEV IKQLLQKFKI 240
ENSPRDFALY IIFGTGEQRK LKKTDVPLLQ RLLQGPSKSN ARIFLMDKDA EEISRDVAPY 300
INFHFSFLES ILQRLDEEEK MEIERIMAKF NTERAFILKC LQSKQAAKTE TTV 353 |
Gene Ontology | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. GO:0042981; P:regulation of apoptotic process; IDA:UniProtKB. GO:0007165; P:signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |