CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008062
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 T-complex protein 1 subunit gamma 
Protein Synonyms/Alias
 TCP-1-gamma; CCT-gamma 
Gene Name
 Cctgamma 
Gene Synonyms/Alias
 CCT-3; Cctg; CG8977 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
198GRLEVDIKRYAKVEKacetylation[1]
224LKGVMINKDVTHPKMacetylation[1]
308LAQHYLLKAGITAIRacetylation[1]
355GAGLFEVKKIGDEYFacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
 Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. 
Sequence Annotation
 DISULFID 368 374 By similarity.  
Keyword
 ATP-binding; Chaperone; Complete proteome; Cytoplasm; Disulfide bond; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 544 AA 
Protein Sequence
MFGGQQPILV LSQNTKRESG RKVQLENIQA GKAIADVIRT CLGPQAMLKM LMDPMGGIVM 60
TNDGNAILRE ITVQHPAAKS MIEIARTQDE EVGDGTTSVI VLAGEMLAAA EPFLQQQIHP 120
TVIIRAYREA LEDIVGHLQS QLSIQLDVKD KAKMADVVKA CVGTKFIGKW SDLAVKIALD 180
AVETVTLSEN GRLEVDIKRY AKVEKIPGGA IEESCVLKGV MINKDVTHPK MRRLIENPRI 240
VLLDCSLEYK KGESQTNVEI IGEQDFTRML QIEEEFVQRI CADIIAVKPD LVFTEKGVSD 300
LAQHYLLKAG ITAIRRLRKT DNLRIARACG ATIVNRTEEL TEKDVGTGAG LFEVKKIGDE 360
YFTFVTECKE PKACTILLRG ASKDILNETE RNLQDALHVA RNLVLEPRLV AGGGAVEMAA 420
SQLLTRKQVK GPYTAVAHAL EIIPRTLAQN CGANTIRALT ALRAKHASHT GDGVCAWGID 480
GESGEIVDMN VKNIWEPLAV KLQTYKTAVE TAILLLRIDD IVSGSKKRGG NEPTNPAAMA 540
QGQE 544 
Gene Ontology
 GO:0005832; C:chaperonin-containing T-complex; ISS:FlyBase.
 GO:0005875; C:microtubule associated complex; IDA:FlyBase.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0042623; F:ATPase activity, coupled; ISS:FlyBase.
 GO:0007052; P:mitotic spindle organization; IMP:FlyBase.
 GO:0006457; P:protein folding; ISS:FlyBase.
 GO:0007430; P:terminal branching, open tracheal system; IMP:FlyBase.
 GO:0060439; P:trachea morphogenesis; IMP:FlyBase. 
Interpro
 IPR012719; Chap_CCT_gamma.
 IPR017998; Chaperone_TCP-1.
 IPR002194; Chaperonin_TCP-1_CS.
 IPR002423; Cpn60/TCP-1.
 IPR027409; GroEL-like_apical_dom.
 IPR027413; GROEL-like_equatorial.
 IPR027410; TCP-1-like_intermed. 
Pfam
 PF00118; Cpn60_TCP1 
SMART
  
PROSITE
 PS00750; TCP1_1
 PS00751; TCP1_2
 PS00995; TCP1_3 
PRINTS
 PR00304; TCOMPLEXTCP1.