CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036512
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Enolase, isoform F 
Protein Synonyms/Alias
  
Gene Name
 Eno 
Gene Synonyms/Alias
 eno1; CG17654; Dmel_CG17654 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
233LISDAIAKAGYTGKIacetylation[1]
427AGVKFAGKSFRKPQ*acetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
 REGION 371 374 Substrate binding (By similarity).
 ACT_SITE 210 210 Proton donor (By similarity).
 ACT_SITE 344 344 Proton acceptor (By similarity).
 BINDING 158 158 Substrate (By similarity).
 BINDING 167 167 Substrate (By similarity).
 BINDING 294 294 Substrate (By similarity).
 BINDING 319 319 Substrate (By similarity).
 BINDING 395 395 Substrate (By similarity).  
Keyword
 Complete proteome; Lyase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 433 AA 
Protein Sequence
MTIKAIKARQ IYDSRGNPTV EVDLTTELGL FRAAVPSGAS TGVHEALELR DNDKANYHGK 60
SVLKAVGHVN DTLGPELIKA NLDVVDQASI DNFMIKLDGT ENKSKFGANA ILGVSLAVAK 120
AGAAKKGVPL YKHIADLAGN KEIILPVPAF NVINGGSHAG NKLAMQEFMI LPTGATSFTE 180
AMKMGSEVYH HLKNVIKAKF GLDATAVGDE GGFAPNIQSN KEALNLISDA IAKAGYTGKI 240
EIGMDVAASE FYKDGQYDLD FKNEKSDKSQ WLPADKLANL YQEFIKDFPI VSIEDPFDQD 300
HWEAWSNLTG CTDIQIVGDD LTVTNPKRIA TAVEKKACNC LLLKVNQIGT VTESIAAHLL 360
AKKNGWGTMV SHRSGETEDS FIGDLVVGLS TGQIKTGAPC RSERLAKYNQ ILRIEEEIGA 420
GVKFAGKSFR KPQ 433 
Gene Ontology
 GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro.
 GO:0000287; F:magnesium ion binding; IEA:InterPro.
 GO:0004634; F:phosphopyruvate hydratase activity; IEA:EC.
 GO:0006096; P:glycolysis; IEA:InterPro. 
Interpro
 IPR000941; Enolase.
 IPR020810; Enolase_C.
 IPR020809; Enolase_CS.
 IPR020811; Enolase_N. 
Pfam
 PF00113; Enolase_C
 PF03952; Enolase_N 
SMART
  
PROSITE
 PS00164; ENOLASE 
PRINTS
 PR00148; ENOLASE.