CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038550
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Cytochrome P450 2C40 
Protein Synonyms/Alias
  
Gene Name
 Cyp2c40 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
134GRIPVFDKVSTGKGIubiquitination[1]
139FDKVSTGKGIGFSHGubiquitination[1]
150FSHGNVWKATRVFTVubiquitination[1]
264GSHNKLFKNHTWIKSubiquitination[1]
270FKNHTWIKSYLLGKIubiquitination[1]
276IKSYLLGKIKEHEESubiquitination[1]
278SYLLGKIKEHEESLDubiquitination[1]
404HEVTCDTKFRNYFIPubiquitination[1]
494LKPLVDPKDIDMTPKubiquitination[1]
501KDIDMTPKHSGFSKIubiquitination[1]
507PKHSGFSKIPPNFQMubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 520 AA 
Protein Sequence
MPKRKILICE CCIKCLECLI IPVSVRRVSM DPFVVLVLCL SFLLVLSLWR QRSARGNLPP 60
GPTPLPIIGN YHLIDMKDIG QCLTNFSKTY GPVFTLYFGS QPIVVLHGYE AIKEALIDHG 120
EEFSGRGRIP VFDKVSTGKG IGFSHGNVWK ATRVFTVNTL RNLGMGKRTI ENKVQEEAQW 180
LMKELKKTNG SPCDPQFIIG CAPCNVICSI VFQNRFDYKD KDFLSLIGKV NECTEILSSP 240
GCQIFNAVPI LIDYCPGSHN KLFKNHTWIK SYLLGKIKEH EESLDVTNPR DFIDYFLIQR 300
RQKNGIEHMD YTIEHLATLV TDLVFGGTET LSSTMRFALL LLMKHTHITA KVQEEIDNVI 360
GRHRSPCMQD RNHMPYTNAM VHEVQRYIDL GPNGVVHEVT CDTKFRNYFI PKGTQVMTSL 420
TSVLHDSTEF PNPEVFDPGH FLDDNGNFKK SDYFVPFSAG KRICVGESLA RMELFLFLTT 480
ILQNFKLKPL VDPKDIDMTP KHSGFSKIPP NFQMCFIPVE 520 
Gene Ontology
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
 GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. 
Interpro
 IPR001128; Cyt_P450.
 IPR017972; Cyt_P450_CS.
 IPR002401; Cyt_P450_E_grp-I. 
Pfam
 PF00067; p450 
SMART
  
PROSITE
 PS00086; CYTOCHROME_P450 
PRINTS
 PR00463; EP450I.
 PR00385; P450.