CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020827
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Short-chain dehydrogenase/reductase family 42E member 1 
Protein Synonyms/Alias
  
Gene Name
 Sdr42e1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
31LGCALNQKGARVILFubiquitination[1]
93SGREQLNKTQIEEVNubiquitination[1]
163TKSIAEKKVLEANGLubiquitination[1]
173EANGLAFKQGDGILRubiquitination[1]
241ILASEALKADKGHVAubiquitination[1]
319LTRTEVYKTGVTHYFubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 ACT_SITE 153 153 Proton acceptor (By similarity).
 BINDING 157 157 NAD (By similarity).  
Keyword
 Complete proteome; Membrane; NAD; Oxidoreductase; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 394 AA 
Protein Sequence
MDSPRFPEET VLITGGGGYF GFRLGCALNQ KGARVILFDI TQPAQNLPEG IKFVCGDIRC 60
LADVETAFQD AEKVACVFHV ASYGMSGREQ LNKTQIEEVN VGGTENILRA CLERGVPRLV 120
YTSTFNVIFG GQVIRNGDES LPYLPLHLHP DHYSRTKSIA EKKVLEANGL AFKQGDGILR 180
TCAIRPAGIY GAGEQRHLPR IVSYIERGLF RFVYGDPQSL VEFVHVDNLA KAHILASEAL 240
KADKGHVASG QPYFISDGRP VNNFEFFRPL VEGLGYTFPS TRLPLTLIYC LAFLVEMTHF 300
IVGRLYNFQP FLTRTEVYKT GVTHYFSLEK AKKELGFEPQ PFDLQEVVEW FKAHGHGRGA 360
AGQDSEFMLW DGILILLLAL SVLTWILPST TLSI 394 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
 GO:0006694; P:steroid biosynthetic process; IEA:InterPro. 
Interpro
 IPR002225; 3Beta_OHSteriod_DH/Estase.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF01073; 3Beta_HSD 
SMART
  
PROSITE
  
PRINTS