UniProt Accession

 RL20A_YEAST; P0CX23; A1YV95; A1YV96; D6W068; P0C2I0; P0C2I1; P47913 

Genbank Protein ID

 Z48756; EF138821; BK006946 

Genbank Nucleotide ID

 CAA88652.1; ABL89189.1; DAA10142.1 

Protein Name

 60S ribosomal protein L20-A 

Protein Synonyms/Alias

 L18a 

Gene Name

 RPL20A 

Gene Synonyms/Alias

 RPL18A; RPL18A2; YMR242C; YM9408.04C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
5	***MAHFKEYQVIGR	acetylation	[1]
23	TESVPEPKLFRMRIF	acetylation	[1]
38	ASNEVIAKSRYWYFL	acetylation	[1]
38	ASNEVIAKSRYWYFL	ubiquitination	[2, 3]
47	RYWYFLQKLHKVKKA	methylation	[4]
53	QKLHKVKKASGEIVS	acetylation	[5]
71	INEAHPTKVKNFGVW	acetylation	[1]
73	EAHPTKVKNFGVWVR	ubiquitination	[3]
92	SGTHNMYKEIRDVSR	acetylation	[1]
92	SGTHNMYKEIRDVSR	ubiquitination	[3]
125	FRSIHILKVAEIEKT	acetylation	[1]
125	FRSIHILKVAEIEKT	ubiquitination	[3, 6]
131	LKVAEIEKTADVKRQ	acetylation	[1]
131	LKVAEIEKTADVKRQ	ubiquitination	[3, 6]
141	DVKRQYVKQFLTKDL	acetylation	[1]
141	DVKRQYVKQFLTKDL	ubiquitination	[3]
146	YVKQFLTKDLKFPLP	acetylation	[1]
146	YVKQFLTKDLKFPLP	ubiquitination	[3]
149	QFLTKDLKFPLPHRV	acetylation	[1]
149	QFLTKDLKFPLPHRV	ubiquitination	[3, 6]
161	HRVQKSTKTFSYKRP	acetylation	[1]
161	HRVQKSTKTFSYKRP	ubiquitination	[3]
166	STKTFSYKRPSTFY*	acetylation	[1]
166	STKTFSYKRPSTFY*	ubiquitination	[3]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis.
 Ziv I, Matiuhin Y, Kirkpatrick DS, Erpapazoglou Z, Leon S, Pantazopoulou M, Kim W, Gygi SP, Haguenauer-Tsapis R, Reis N, Glickman MH, Kleifeld O.
 Mol Cell Proteomics. 2011 May;10(5):M111.009753. [PMID: 21427232]
 [3] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [4] Identification of arginine- and lysine-methylation in the proteome of Saccharomyces cerevisiae and its functional implications.
 Pang CN, Gasteiger E, Wilkins MR.
 BMC Genomics. 2010 Feb 5;11:92. [PMID: 20137074]
 [5] Preparative peptide isoelectric focusing as a tool for improving the identification of lysine-acetylated peptides from complex mixtures.
 Xie H, Bandhakavi S, Roe MR, Griffin TJ.
 J Proteome Res. 2007 May;6(5):2019-26. [PMID: 17397211]
 [6] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 

Functional Description

  

Sequence Annotation

 MOD_RES 32 32 Phosphoserine.  

Keyword

 3D-structure; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 172 AA 

Protein Sequence

Gene Ontology

 GO:0022625; C:cytosolic large ribosomal subunit; TAS:SGD.
 GO:0003735; F:structural constituent of ribosome; TAS:SGD.
 GO:0002181; P:cytoplasmic translation; TAS:SGD. 

Interpro

 IPR021138; Ribosomal_L18a.
 IPR023573; Ribosomal_L18a/LX. 

Pfam

 PF01775; Ribosomal_L18ae 

SMART

  

PROSITE

  

PRINTS