CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032500
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Enolase 2 
Protein Synonyms/Alias
 Enolase, putative 
Gene Name
 TGGT1_107040, TGME49_068850, TGVEG_015860 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
378IEKAVQEKACNGLLLacetylation[1]
407CQLAQKNKWGVMVSHacetylation[1, 2]
Reference
 [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842]
 [2] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907] 
Functional Description
  
Sequence Annotation
 REGION 413 416 Substrate binding (By similarity).
 ACT_SITE 248 248 Proton donor (By similarity).
 ACT_SITE 386 386 Proton acceptor (By similarity).
 BINDING 196 196 Substrate (By similarity).
 BINDING 205 205 Substrate (By similarity).
 BINDING 334 334 Substrate (By similarity).
 BINDING 361 361 Substrate (By similarity).
 BINDING 437 437 Substrate (By similarity).  
Keyword
 Complete proteome; Lyase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 475 AA 
Protein Sequence
MFRLLVPTYY SYSVPLRFPF CKIYRYSTSN KMVAIKDITA RQILDSRGNP TVEVDLLTDG 60
GCFRAAVPSG ASTGIYEALE LRDKDQTKFM GKGVMKAVEN IHKIIKPALI GKDPCDQKGI 120
DKLMVEELDG TKNEWGWCKS KLGANAILAV SMACCRAGAA AKGMPLYKYI ATLAGNPTDK 180
MVMPVPFFNV INGGSHAGNK VAMQEFMIAP VGASTIQEAI QIGAEVYQHL KVVIKKKYGL 240
DATNVGDEGG FAPNISGATE ALDLLMEAIK VSGHEGKVKI AADVAASEFF LQDDKVYDLD 300
FKTPNNDKSQ RKTGEELRNL YKDLCQKYPF VSIEDPFDQD DFHSYAQLTN EVGEKVQIVG 360
DDLLVTNPTR IEKAVQEKAC NGLLLKVNQI GTVSESIEAC QLAQKNKWGV MVSHRSGETE 420
DSFIADLVVG LRTGQIKTGA PCRSERLCKY NQLMRIEESL GSDCQYAGAG FRHPN 475 
Gene Ontology
 GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro.
 GO:0000287; F:magnesium ion binding; IEA:InterPro.
 GO:0004634; F:phosphopyruvate hydratase activity; IEA:EC.
 GO:0006096; P:glycolysis; IEA:InterPro. 
Interpro
 IPR000941; Enolase.
 IPR020810; Enolase_C.
 IPR020809; Enolase_CS.
 IPR020811; Enolase_N. 
Pfam
 PF00113; Enolase_C
 PF03952; Enolase_N 
SMART
  
PROSITE
 PS00164; ENOLASE 
PRINTS
 PR00148; ENOLASE.