CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019610
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pecanex-like protein 1 
Protein Synonyms/Alias
 Pecanex homolog 
Gene Name
 PCNX 
Gene Synonyms/Alias
 KIAA0805; KIAA0995; PCNXL1 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
714LMAPESIKPLTTSKSacetylation[1]
1528WERDYNTKRVDHSNTubiquitination[2]
1974RGSIQNAKQALRNMIubiquitination[2, 3]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 CARBOHYD 109 109 N-linked (GlcNAc...) (Potential).
 CARBOHYD 215 215 N-linked (GlcNAc...) (Potential).
 CARBOHYD 348 348 N-linked (GlcNAc...) (Potential).
 CARBOHYD 394 394 N-linked (GlcNAc...) (Potential).
 CARBOHYD 702 702 N-linked (GlcNAc...) (Potential).
 CARBOHYD 852 852 N-linked (GlcNAc...) (Potential).
 CARBOHYD 863 863 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1091 1091 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1155 1155 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1579 1579 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1720 1720 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1982 1982 N-linked (GlcNAc...) (Potential).
 CARBOHYD 2062 2062 N-linked (GlcNAc...) (Potential).
 CARBOHYD 2072 2072 N-linked (GlcNAc...) (Potential).
 CARBOHYD 2234 2234 N-linked (GlcNAc...) (Potential).
 CARBOHYD 2260 2260 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Complete proteome; Glycoprotein; Membrane; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2341 AA 
Protein Sequence
MGSQTLQILR QGVWAALSGG WYYDPHQATF VNALHLYLWL FLLGLPFTLY MALPSTMIIV 60
AVYCPVIAAV FIVLKMVNYR LHRALDAGEV VDRTANEFTD QRTKAEQGNC STRRKDSNGP 120
SDPGGGIEMS EFIREATPPV GCSSRNSYAG LDPSNQIGSG SSRLGTAATI KGDTDTAKTS 180
DDISLSLGQS SSLCKEGSEE QDLAADRKLF RLVSNDSFIS IQPSLSSCGQ DLPRDFSDKV 240
NLPSHNHHHH VDQSLSSACD TEVASLVPLH SHSYRKDHRP RGVPRTSSSA VAFPDTSLND 300
FPLYQQRRGL DPVSELESSK PLSGSKESLV ENSGLSGEFQ LAGDLKINTS QPPTKSGKSK 360
PLKAEKSMDS LRSLSTRSSG STESYCSGTD RDTNSTVSSY KSEQTSSTHI ESILSEHEES 420
PKAGTKSGRK KECCAGPEEK NSCASDKRTS SEKIAMEAST NSGVHEAKDP TPSDEMHNQR 480
GLSTSASEEA NKNPHANEFT SQGDRPPGNT AENKEEKSDK SAVSVDSKVR KDVGGKQKEG 540
DVRPKSSSVI HRTASAHKSG RRRTGKKRAS SFDSSRHRDY VCFRGVSGTK PHSAIFCHDE 600
DSSDQSDLSR ASSVQSAHQF SSDSSSSTTS HSCQSPEGRY SALKTKHTHK ERGTDSEHTH 660
KAHLVPEGTS KKRATRRTSS TNSAKTRARV LSLDSGTVAC LNDSNRLMAP ESIKPLTTSK 720
SDLEAKEGEV LDELSLLGRA SQLETVTRSR NSLPNQVAFP EGEEQDAVSG AAQASEEAVS 780
FRRERSTFRR QAVRRRHNAG SNPTPPTLLI GSPLSLQDGQ QGQQSTAQVK VQSRPPSQAA 840
VLSASASLLV RNGSVHLEAS HDNASAVGGS SLHDELGKFS STLYETGGCD MSLVNFEPAA 900
RRASNICDTD SHVSSSTSVR FYPHDVLSLP QIRLNRLLTI DTDLLEQQDI DLSPDLAATY 960
GPTEEAAQKV KHYYRFWILP QLWIGINFDR LTLLALFDRN REILENVLAV ILAILVAFLG 1020
SILLIQGFFR DIWVFQFCLV IASCQYSLLK SVQPDSSSPR HGHNRIIAYS RPVYFCICCG 1080
LIWLLDYGSR NLTATKFKLY GITFTNPLVF ISARDLVIVF TLCFPIVFFI GLLPQVNTFV 1140
MYLCEQLDIH IFGGNATTSL LAALYSFICS IVAVALLYGL CYGALKDSWD GQHIPVLFSI 1200
FCGLLVAVSY HLSRQSSDPS VLFSLVQSKI FPKTEEKNPE DPLSEVKDPL PEKLRNSVSE 1260
RLQSDLVVCI VIGVLYFAIH VSTVFTVLQP ALKYVLYTLV GFVGFVTHYV LPQVRKQLPW 1320
HCFSHPLLKT LEYNQYEVRN AATMMWFEKL HVWLLFVEKN IIYPLIVLNE LSSSAETIAS 1380
PKKLNTELGA LMITVAGLKL LRSSFSSPTY QYVTVIFTVL FFKFDYEAFS ETMLLDLFFM 1440
SILFNKLWEL LYKLQFVYTY IAPWQITWGS AFHAFAQPFA VPHSAMLFIQ AAVSAFFSTP 1500
LNPFLGSAIF ITSYVRPVKF WERDYNTKRV DHSNTRLASQ LDRNPGSDDN NLNSIFYEHL 1560
TRSLQHSLCG DLLLGRWGNY STGDCFILAS DYLNALVHLI EIGNGLVTFQ LRGLEFRGTY 1620
CQQREVEAIT EGVEEDEGFC CCEPGHIPHM LSFNAAFSQR WLAWEVIVTK YILEGYSITD 1680
NSAASMLQVF DLRKVLTTYY VKGIIYYVTT SSKLEEWLAN ETMQEGLRLC ADRNYVDVDP 1740
TFNPNIDEDY DHRLAGISRE SFCVIYLNWI EYCSSRRAKP VDVDKDSSLV TLCYGLCVLG 1800
RRALGTASHH MSSNLESFLY GLHALFKGDF RISSIRDEWI FADMELLRKV VVPGIRMSIK 1860
LHQDHFTSPD EYDDPTVLYE AIVSHEKNLV IAHEGDPAWR SAVLANSPSL LALRHVMDDG 1920
TNEYKIIMLN RRYLSFRVIK VNKECVRGLW AGQQQELVFL RNRNPERGSI QNAKQALRNM 1980
INSSCDQPIG YPIFVSPLTT SYSDSHEQLK DILGGPISLG NIRNFIVSTW HRLRKGCGAG 2040
CNSGGNIEDS DTGGGTSCTG NNATTANNPH SNVTQGSIGN PGQGSGTGLH PPVTSYPPTL 2100
GTSHSSHSVQ SGLVRQSPAR ASVASQSSYC YSSRHSSLRM STTGFVPCRR SSTSQISLRN 2160
LPSSIQSRLS MVNQMEPSGQ SGLACVQHGL PSSSSSSQSI PACKHHTLVG FLATEGGQSS 2220
ATDAQPGNTL SPANNSHSRK AEVIYRVQIV DPSQILEGIN LSKRKELQWP DEGIRLKAGR 2280
NSWKDWSPQE GMEGHVIHRW VPCSRDPGTR SHIDKAVLLV QIDDKYVTVI ETGVLELGAE 2340
V 2341 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR007735; Pecanex. 
Pfam
 PF05041; Pecanex_C 
SMART
  
PROSITE
  
PRINTS