CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006606
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 SIT4-associating protein SAP190 
Protein Synonyms/Alias
  
Gene Name
 SAP190 
Gene Synonyms/Alias
 YKR028W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
145DEETDSAKKPEIIEGubiquitination[1]
312LKVISTDKPDSPTGVubiquitination[1]
580SSVKLDVKSDAKVVEubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Positive regulator of protein phosphatase SIT4. Involved in the general amino acid control (GAAC) response regulated by TOR. Involved in the dephosphorylation of the elongator complex subunit IKI3. 
Sequence Annotation
 MOD_RES 774 774 Phosphoserine.
 MOD_RES 857 857 Phosphoserine.
 MOD_RES 862 862 Phosphoserine.
 MOD_RES 892 892 Phosphoserine.
 MOD_RES 990 990 Phosphothreonine.
 MOD_RES 991 991 Phosphoserine.  
Keyword
 Cell cycle; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1033 AA 
Protein Sequence
MSGSFWKFGQ DYSIESPVSK ILNSAFIKIN KDQDDDVPTG TCEENIADDE DNSSHDYAAS 60
EDNVVNENEE KEEENTLPTT ESEYENYRPN LDVLDDLLDD DELYTELMCS NFKLLIFLKY 120
PDVLSKLIEY VTNEKILDEE TDSAKKPEII EGVNDHPILI ERDRKDKKED AEEGGDSEET 180
TNDSDHDSGD ERSVDSEETS ITLPPESEEQ VETRRARIAA EILSADVWPI SAAIMQNKDL 240
LGRLWSILDH PAPLPIPAST YFMKINERLL DMDITGMLEF ILSRDSLVAR FLTHVDNPSL 300
MDFLLKVIST DKPDSPTGVI KILKSQELIP KLLDHLNPEY GISTQSAAGD FIKAFVTLST 360
NSSNELASGI GPNELTRQLV SEEMIEKLIK IMLKGGTSLS NGVGIIIELI RKNNSDYDFI 420
QLVYTTLESH PPTDRDPIHL IHLVKLFAKH MPDFADMLDK TKLPLMEMPF GNIEPLGFER 480
FKICELIAEL LHCSNMTLLN EPNGEMIAQE RDIERAKELE TSTEKENITA IVDNKSSYYD 540
KDCVEKDITE NLGALQINNQ GSEEDELNDT GVSSVKLDVK SDAKVVEGLE NDASGVELYD 600
ETLSDTESVR ECLREKPLVG DRLKIALEDT KILISILDMF TEFPWNNFLH NVIFDIAQQI 660
FNGPLKTGYN RFLLKDYLVD AYLTKKIVDA DKACQDYEKK TGLRYGYMGH LTLVAEEISK 720
FKEYIDEMKL TFCNTAVSDR LEEPFWKEYS ETILADTREK YNTVLGDFGN DQESDDDVIR 780
NSDSEDIIGD TEGNENYGNG ENDELLSNGH DSGNMDLYYN FNNNENEENE EDYAEYSDVD 840
NKNYYNNVET NDDDYDSDDG KSKSAESEFT DKISEHRDGN SLYNEDNDEN GSDKWTSGTS 900
LFPPDHFPSR SQPSDPKLQD QNIFHHQFDF EGVGDDDDYM DPNDDGQSYA RPGNPLYTTP 960
KTPPRPKTIL FNSLSALDNN GEDEEVALGT SVDDRMDNEI SSDEEDSEDE DEENDMGNEE 1020
GYSLYRSRSK EAF 1033 
Gene Ontology
 GO:0005737; C:cytoplasm; IPI:SGD.
 GO:0016311; P:dephosphorylation; IMP:SGD.
 GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.
 GO:0031929; P:TOR signaling cascade; IMP:SGD.
 GO:0002098; P:tRNA wobble uridine modification; IGI:SGD. 
Interpro
 IPR007587; SAPS. 
Pfam
 PF04499; SAPS 
SMART
  
PROSITE
  
PRINTS