CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028660
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Bcl-2-like protein 1 
Protein Synonyms/Alias
  
Gene Name
 Bcl2l1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
87VIPMAAVKQALREAGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 96 AA 
Protein Sequence
MSQSNRELVV DFLSYKLSQK GYSWSQFSDV EENRTEAPEE TEAERETPSA INGNPSWHLA 60
DSPAVNGATG HSSSLDAREV IPMAAVKQAL REAGDE 96 
Gene Ontology
 GO:0097136; C:Bcl-2 family protein complex; IEA:Compara.
 GO:0005813; C:centrosome; IEA:Compara.
 GO:0005829; C:cytosol; IDA:MGI.
 GO:0031966; C:mitochondrial membrane; IDA:MGI.
 GO:0071839; P:apoptotic process in bone marrow; IMP:MGI.
 GO:0008283; P:cell proliferation; IDA:MGI.
 GO:0060154; P:cellular process regulating host cell cycle in response to virus; IMP:MGI.
 GO:0071312; P:cellular response to alkaloid; IDA:MGI.
 GO:0071230; P:cellular response to amino acid stimulus; IMP:MGI.
 GO:0071480; P:cellular response to gamma radiation; IMP:MGI.
 GO:0000910; P:cytokinesis; IEA:Compara.
 GO:0009566; P:fertilization; IGI:MGI.
 GO:0007281; P:germ cell development; IMP:MGI.
 GO:0040007; P:growth; IMP:MGI.
 GO:0097284; P:hepatocyte apoptotic process; IMP:MGI.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IMP:MGI.
 GO:0008584; P:male gonad development; IMP:MGI.
 GO:2000811; P:negative regulation of anoikis; IEA:Compara.
 GO:0090005; P:negative regulation of establishment of protein localization to plasma membrane; IEA:Compara.
 GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IEA:Compara.
 GO:0043524; P:negative regulation of neuron apoptotic process; IDA:MGI.
 GO:0051402; P:neuron apoptotic process; IMP:MGI.
 GO:0001541; P:ovarian follicle development; IMP:MGI.
 GO:0043065; P:positive regulation of apoptotic process; IDA:MGI.
 GO:0008284; P:positive regulation of cell proliferation; IDA:MGI.
 GO:0046902; P:regulation of mitochondrial membrane permeability; IEA:Compara.
 GO:0051881; P:regulation of mitochondrial membrane potential; IEA:Compara.
 GO:0001836; P:release of cytochrome c from mitochondria; IGI:MGI.
 GO:0046898; P:response to cycloheximide; IDA:MGI.
 GO:0034097; P:response to cytokine stimulus; ISO:MGI.
 GO:0007283; P:spermatogenesis; IGI:MGI. 
Interpro
 IPR013279; Apop_reg_BclX.
 IPR003093; Bcl2_BH4.
 IPR020731; Bcl2_BH4_motif_CS.
 IPR026298; Blc2_fam. 
Pfam
 PF02180; BH4 
SMART
 SM00265; BH4 
PROSITE
 PS01260; BH4_1
 PS50063; BH4_2 
PRINTS
 PR01864; APOPREGBCLX.