UniProt Accession

 NEMR_ECOLI; P67430; P76189; Q2MB64 

Genbank Protein ID

 U00096; AP009048 

Genbank Nucleotide ID

 AAC74721.3; BAE76492.1 

Protein Name

 HTH-type transcriptional repressor NemR 

Protein Synonyms/Alias

  

Gene Name

 nemR 

Gene Synonyms/Alias

 ydhM; b1649; JW5874 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
42	LKTAEVPKGSFYHYF	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Represses the transcription of the nemRA operon by binding to the nemR box. 

Sequence Annotation

 DOMAIN 7 67 HTH tetR-type.
 DNA_BIND 30 49 H-T-H motif (Potential).  

Keyword

 Complete proteome; DNA-binding; Reference proteome; Repressor; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 199 AA 

Protein Sequence

Gene Ontology

 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:EcoCyc.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:EcoCyc.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR009057; Homeodomain-like.
 IPR001647; HTH_TetR.
 IPR015893; Tet_transcr_reg_TetR-like_C.
 IPR011075; Tet_transcr_reg_TetR-rel_C. 

Pfam

 PF00440; TetR_N 

SMART

  

PROSITE

 PS01081; HTH_TETR_1
 PS50977; HTH_TETR_2 

PRINTS