| Tag | Content |
|---|
| CPLM ID | CPLM-016108 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Dipeptidyl peptidase 8 |
Protein Synonyms/Alias | DP8; Dipeptidyl peptidase VIII; DPP VIII |
Gene Name | Dpp8 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 382 | AGWTPEGKHAWSILL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. May play a role in T-cell activation and immune function (By similarity). |
Sequence Annotation | ACT_SITE 749 749 Charge relay system (By similarity).
ACT_SITE 827 827 Charge relay system (By similarity).
ACT_SITE 859 859 Charge relay system (By similarity).
MOD_RES 325 325 Phosphotyrosine. |
Keyword | Aminopeptidase; Complete proteome; Cytoplasm; Hydrolase; Phosphoprotein; Protease; Reference proteome; Serine protease. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 892 AA |
Protein Sequence | MKIPSGRCNM AAAMETEQLG VEIFETAECE EGNGESQDRP KLEPFYVERY SWSQLKKLLA 60
DTRKYHGYMM AKAPHDFMFV KRTDPDGPHS DRVYYLAMSG ENRENTLFYS EIPKTINRAA 120
VLMLSWKPLL DLFQATLDYG MYSREEELLR ERKRIGTVGI AAYDYHPGSG TFLFQAGSGI 180
YHIKDGGPHG FTQQPLRPNL VETSCPNIRM DPKLCPADPD WIAFIHSNDI WISNLVTREE 240
RRITYVHNEL ANMEEDPRSA GVATFVLQEE FDRYSGYWWC PQAERTPSGG KILRILYEEN 300
DESEVEIIHV TSPMLETRRA DSFRYPKTGT ANPKVTFKMS EIVVDAAGGI IDVIDKELVQ 360
PFEILFEGVE YIARAGWTPE GKHAWSILLD RSQTHLQIVL ISPELFIPVE DDAMDRQRLI 420
ESVPDSVTPL IIYEETTDIW INIHDIFHVF PQTHEDEIEF IFASECKTGF RHLYKITSIL 480
KESKYKRSSG GLPAPSDFKC PIKEEITITS GEWEVLGRHG SNIWVDEARK LVYFEGTKDS 540
PLEHHLYVTS YANPGEVVRL TDRGYSHSCC LSRHCDFFIS KYSNQKNPHC VSLYKLSSPE 600
DDPVHKTKEF WATILDSAGP LPDYTPPEIF SFESTTGFTL YGMLYKPHDL QPGKKYPTVL 660
FIYGGPQVQL VNNRFKGVKY FRLNTLASLG YVVVVIDNRG SCHRGLKFEG AFKYKMGQIE 720
IDDQVEGLQY LASQYDFIDL DRVGIHGWSY GGYLSLMALM QRSDIFRVAI AGAPVTLWIF 780
YDTGYTERYM GHPDQNEQGY YLGSVAMQAE KFPSEPNRLL LLHGFLDENV HFAHTSILLS 840
FLVRAGKPYD LQIYPQERHS IRVPESGEHY ELHLLHYLQE NLGSRIAALK VI 892 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |