CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015953
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 WD repeat-containing protein 53 
Protein Synonyms/Alias
  
Gene Name
 WDR53 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
127ILDLENKKVIRSLKRubiquitination[1]
277ANSEVEKKQKSPTKRubiquitination[1]
326LNIEHGEKVNWLLGTubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 REPEAT 8 46 WD 1.
 REPEAT 92 131 WD 2.
 REPEAT 134 174 WD 3.
 REPEAT 195 234 WD 4.
 REPEAT 239 278 WD 5.  
Keyword
 Complete proteome; Polymorphism; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 358 AA 
Protein Sequence
MAVKWTGGHS SPVLCLNASK EGLLASGAEG GDLTAWGEDG TPLGHTRFQG ADDVTSVLFS 60
PSCPTKLYAS HGETISVLDV RSLKDSLDHF HVNEEEINCL SLNQTENLLA SADDSGAIKI 120
LDLENKKVIR SLKRHSNICS SVAFRPQRPQ SLVSCGLDMQ VMLWSLQKAR PLWITNLQED 180
ETEEMEGPQS PGQLLNPALA HSISVASCGN IFSCGAEDGK VRIFRVMGVK CEQELGFKGH 240
TSGVSQVCFL PESYLLLTGG NDGKITLWDA NSEVEKKQKS PTKRTHRKKP KRGTCTKQGG 300
NTNASVTDEE EHGNILPKLN IEHGEKVNWL LGTKIKGHQN ILVADQTSCI SVYPLNEF 358 
Gene Ontology
  
Interpro
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS