CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021699
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ran guanine nucleotide release factor 
Protein Synonyms/Alias
 RanGNRF; Ran-binding protein MOG1 
Gene Name
 RANGRF 
Gene Synonyms/Alias
 MOG1; RANGNRF; HSPC165; HSPC236; MDS5 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
113SGKQQIAKENQQVRAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May regulate the intracellular trafficking of RAN. In cardiac cells seems to regulate the cell surface localization of SCN5A. 
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Guanine-nucleotide releasing factor; Nucleus; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 186 AA 
Protein Sequence
MEPTRDCPLF GGAFSAILPM GAIDVSDLRP VPDNQEVFCH PVTDQSLIVE LLELQAHVRG 60
EAAARYHFED VGGVQGARAV HVESVQPLSL ENLALRGRCQ EAWVLSGKQQ IAKENQQVRA 120
RECVMSWKGG SGDAEIQVSI LTLIPLGSKG RDTSSGLAEA APVPD 165 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0014704; C:intercalated disc; ISS:BHF-UCL.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
 GO:0017080; F:sodium channel regulator activity; IDA:BHF-UCL.
 GO:2000010; P:positive regulation of protein localization to cell surface; IDA:BHF-UCL.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0042391; P:regulation of membrane potential; IDA:BHF-UCL.
 GO:2000649; P:regulation of sodium ion transmembrane transporter activity; IDA:BHF-UCL. 
Interpro
 IPR007681; Mog1.
 IPR016123; Mog1/PsbP_a/b/a-sand. 
Pfam
 PF04603; Mog1 
SMART
  
PROSITE
  
PRINTS