CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016027
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Syntaphilin 
Protein Synonyms/Alias
  
Gene Name
 Snph 
Gene Synonyms/Alias
 Kiaa0374 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
144DTEIDDLKTQLSRMQubiquitination[1]
186KQVIDTVKNNLIDKDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Inhibits SNARE complex formation by absorbing free syntaxin-1 (By similarity). 
Sequence Annotation
 MOD_RES 20 20 Phosphoserine.
 MOD_RES 293 293 Phosphotyrosine.  
Keyword
 Alternative splicing; Cell junction; Coiled coil; Complete proteome; Membrane; Phosphoprotein; Reference proteome; Synapse; Synaptosome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 495 AA 
Protein Sequence
MAMSLQGSRR ASAGSRSGGT LGRSGLAVFA QCPQVPASQN EQRPLLPASR RTSPPVSVRD 60
AYGTSSLSSS SNSGSCKGSD SSPTPRRSMK YTLCSDNHGI KPPTPEQYLT PLQQKEVCIR 120
HLKARLKDTQ DRLQDRDTEI DDLKTQLSRM QEDWIEEECH RVEAQLALKE ARKEIRQLKQ 180
VIDTVKNNLI DKDKGLQKYF VDINIQNKKL ETLLHSMEVA QNGVAKEEGT GESAGGSPAR 240
SLTRSSTYTK LSDPAVCGDR QPGDPSNTSA EDGADSGYVA ADDTLSRTDA LEASSLLSSG 300
VDCGLEEASL HSSFNLGPRF PASNTYEKLL CGMEAGVQVS CMQERAIQTD FVQYQPDLNT 360
ILEKVGQAQV CGSVLKDRHS ELDPHPSGPR DPDSAVVVTV GDELEAPEPI TCGPATHRPA 420
VNSNPGLPVS VVCPVEEEEE EAAAATTTEK EPKSYWSRHY IVDLLAVVVP AVPTVAWLCR 480
SQRRQGQPIY NISSLLRGCC TVALHSIRRI SCRSLGQPSS STAGGSQL 528 
Gene Ontology
 GO:0030054; C:cell junction; IEA:UniProtKB-KW.
 GO:0005881; C:cytoplasmic microtubule; ISS:UniProtKB.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0031966; C:mitochondrial membrane; IEA:Compara.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0043005; C:neuron projection; IEA:UniProtKB-SubCell.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0042734; C:presynaptic membrane; IEA:Compara.
 GO:0007420; P:brain development; IEA:Compara.
 GO:0030182; P:neuron differentiation; IEA:Compara. 
Interpro
 IPR026196; Syntaphilin. 
Pfam
  
SMART
  
PROSITE
  
PRINTS