CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015236
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Atlastin-2 
Protein Synonyms/Alias
 ADP-ribosylation factor-like protein 6-interacting protein 2; ARL-6-interacting protein 2; Aip-2 
Gene Name
 Atl2 
Gene Synonyms/Alias
 Arl6ip2 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
270LEKRLQVKQNQHEELubiquitination[1]
314PSFDGRLKDIDEDFKubiquitination[1]
321KDIDEDFKRELRNLVubiquitination[1]
357RDLVEYFKAYIKIYQubiquitination[1]
422ERKHLDLKEVALKQFubiquitination[1]
427DLKEVALKQFRSVKKubiquitination[1]
461ETYANFIKHNDGKNIubiquitination[1]
567QSVTNSIKAGLTDQVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 GTPase tethering membranes through formation of trans- homooligomer and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis (By similarity). 
Sequence Annotation
 NP_BIND 101 108 GTP (Potential).
 NP_BIND 173 177 GTP (Potential).
 MOD_RES 24 24 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Endoplasmic reticulum; GTP-binding; Hydrolase; Membrane; Nucleotide-binding; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 583 AA 
Protein Sequence
MAEGDEAARR QQPQQGLRRR RQTSDSSVGV NHVSSTTSLG EDYEDDDLVN SDEVMKKPCP 60
VQIVLAHEDD HNFELDEEAL EQILLQEHIR DLNIVVVSVA GAFRKGKSFL LDFMLRYMYN 120
KDSQSWIGGN NEPLTGFTWR GGCERETTGI QVWNEVFVID RPNGTKVAVL LMDTQGAFDS 180
QSTIKDCATV FALSTMTSSV QVYNLSQNIQ EDDLQHLQLF TEYGRLAMEE IYQKPFQTLM 240
FLIRDWSYPY EHSYGLEGGK QFLEKRLQVK QNQHEELQNV RKHIHNCFSN LGCFLLPHPG 300
LKVATNPSFD GRLKDIDEDF KRELRNLVPL LLAPENLVEK EISGSKVTCR DLVEYFKAYI 360
KIYQGEELPH PKSMLQATAE ANNLAAVAGA RDVYCKSMEQ VCGGDKPYIA PSDLERKHLD 420
LKEVALKQFR SVKKMGGDEF CRRYQDQLEA EIEETYANFI KHNDGKNIFY AARTPATLFA 480
VMFAMYIISG LTGFIGLNSI AVLCNLVMGL ALTSLCTWAY VKYSGEFREI GTMIDQIAET 540
LWEQVLKPLG DNLMEENIRQ SVTNSIKAGL TDQVSHHARL KTD 583 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; ISS:UniProtKB.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0042802; F:identical protein binding; ISS:UniProtKB.
 GO:0007029; P:endoplasmic reticulum organization; ISS:UniProtKB.
 GO:0007030; P:Golgi organization; ISS:UniProtKB.
 GO:0006184; P:GTP catabolic process; IEA:GOC.
 GO:0051260; P:protein homooligomerization; ISS:UniProtKB. 
Interpro
 IPR003191; Guanylate-bd_C.
 IPR015894; Guanylate-bd_N.
 IPR027417; P-loop_NTPase. 
Pfam
 PF02263; GBP 
SMART
  
PROSITE
  
PRINTS