UniProt Accession

 MYL1_RAT; P02600; P02601 

Genbank Protein ID

 L00088; K02423; K02426; L00085; L00086; L00087; L00088; K02424; K02425; L00085; L00086; L00087; M12021; M12017; M12018; M12019; M12020; M12021; M12018; M12019; M12020 

Genbank Nucleotide ID

 AAA98533.1; AAA98533.1; AAA98533.1; AAA98533.1; AAA98533.1; AAA98533.1; AAA98534.1; AAA98534.1; AAA98534.1; AAA98534.1; AAA98534.1; AAA98534.1; AAA41622.1; AAA41622.1; AAA41622.1; AAA41622.1; AAA41622.1; AAA41623.1; AAA41623.1; AAA41623.1; AAA41623.1 

Protein Name

 Myosin light chain 1/3, skeletal muscle isoform 

Protein Synonyms/Alias

 MLC1/MLC3; MLC1F/MLC3F; Myosin light chain alkali 1/2; Myosin light chain A1/A2 

Gene Name

 Myl1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
27	APAPAPAKPKEEKID	acetylation	[1]
39	KIDLSAIKIEFSKEQ	acetylation	[1]
51	KEQQEEFKEAFLLFD	acetylation	[1]
64	FDRTGECKITLSQVG	acetylation	[1]
87	NPTNAEVKKVLGNPS	acetylation	[1]
101	SNEEMNAKKIEFEQF	acetylation	[1]
102	NEEMNAKKIEFEQFL	acetylation	[1]
119	MQAISNNKDQGGYED	acetylation	[1]
136	EGLRVFDKEGNGTVM	acetylation	[1]
157	VLATLGEKMKEEEVE	ubiquitination	[2]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 

Functional Description

 Regulatory light chain of myosin. Does not bind calcium. 

Sequence Annotation

 DOMAIN 45 80 EF-hand 1.
 DOMAIN 122 157 EF-hand 2.
 DOMAIN 157 189 EF-hand 3.
 MOD_RES 2 2 N,N,N-trimethylalanine (By similarity).  

Keyword

 Acetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Methylation; Motor protein; Muscle protein; Myosin; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 189 AA 

Protein Sequence

Gene Ontology

 GO:0043292; C:contractile fiber; IDA:RGD.
 GO:0030016; C:myofibril; IEA:Compara.
 GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0060048; P:cardiac muscle contraction; IMP:RGD. 

Interpro

 IPR011992; EF-hand-like_dom.
 IPR002048; EF_hand_dom. 

Pfam

 PF13405; EF_hand_4 

SMART

 SM00054; EFh 

PROSITE

 PS50222; EF_HAND_2 

PRINTS