UniProt Accession

 ORN_YEAST; P54964; D6VY61; E9P909 

Genbank Protein ID

 L47977; X94607; Z73231; AY693005; BK006945 

Genbank Nucleotide ID

 AAA98633.1; CAA64306.1; CAA97590.1; AAT93024.1; DAA09377.1 

Protein Name

 Oligoribonuclease, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 REX2 

Gene Synonyms/Alias

 YNT20; YLR059C; L2159 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
111	YGPEVMNKMNEWCIE	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity). 

Sequence Annotation

 DOMAIN 55 227 Exonuclease.
 ACT_SITE 184 184 Potential.  

Keyword

 Complete proteome; Exonuclease; Hydrolase; Mitochondrion; Nuclease; Reference proteome; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 269 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0000175; F:3'-5'-exoribonuclease activity; IMP:SGD.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IGI:SGD.
 GO:0000002; P:mitochondrial genome maintenance; IMP:SGD.
 GO:0034475; P:U4 snRNA 3'-end processing; IMP:SGD.
 GO:0034476; P:U5 snRNA 3'-end processing; IGI:SGD. 

Interpro

 IPR006055; Exonuclease.
 IPR013520; Exonuclease_RNaseT/DNA_pol3.
 IPR012337; RNaseH-like_dom. 

Pfam

 PF00929; RNase_T 

SMART

 SM00479; EXOIII 

PROSITE

  

PRINTS