| Tag | Content |
|---|
| CPLM ID | CPLM-022688 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Nucleolar protein 58 |
Protein Synonyms/Alias | Nopp140-associated protein of 65 kDa; Nucleolar protein 5 |
Gene Name | Nop58 |
Gene Synonyms/Alias | Nap65; Nol5; Nop5 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 411 | RKISGTGKALAKAEK | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Required for 60S ribosomal subunit biogenesis (By similarity). |
Sequence Annotation | DOMAIN 282 400 Nop.
MOD_RES 109 109 Phosphoserine (By similarity).
MOD_RES 351 351 Phosphoserine (By similarity).
MOD_RES 507 507 Phosphoserine (By similarity).
MOD_RES 519 519 Phosphoserine (By similarity).
CROSSLNK 467 467 Glycyl lysine isopeptide (Lys-Gly)
CROSSLNK 502 502 Glycyl lysine isopeptide (Lys-Gly) |
Keyword | Complete proteome; Direct protein sequencing; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; Ribosome biogenesis; Ubl conjugation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 534 AA |
Protein Sequence | MLVLFETSVG YAIFKVLNEK KLQEVDSLWK EFETPEKANK IVKLKHFEKF QDTAEALAAF 60
TALMEGKINK QLKKVLKKIV KEAHEPLAVA DAKLGGVIKE KLNLSCIHSP VVNELMRGIR 120
SQMDGLIPGV EPREMAAMCL GLAHSLSRYR LKFSADKVDT MIVQAISLLD DLDKELNNYI 180
MRCREWYGWH FPELGKIISD NLTYCKCLQK VGDRKNYASA TLSEFLSEEV EAEVKAAAEI 240
SMGTEVSEED ICNILHLCTQ VIEISEYRTQ LYEYLQNRMM AIAPNVTVMV GELVGARLIA 300
HAGSLLNLAK HAASTVQILG AEKALFRALK SRRDTPKYGL IYHASLVGQT SPKHKGKISR 360
MLAAKTVLAI RYDAFGEDSS SAMGAENRAK LEARLRILED RGIRKISGTG KALAKAEKYE 420
HKSEVKTYDP SGDSTLPTCS KKRKIEEVDK EDEITEKKAK KAKIKIKAEV EEEMEEAEEE 480
QVVEEEPTVK KKKKKDKKKH IKEEPLSEEE PCTSTAVPSP EKKKKKKKKK DAED 534 |
Gene Ontology | GO:0015030; C:Cajal body; IEA:Compara. GO:0005737; C:cytoplasm; IEA:Compara. GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. GO:0070761; C:pre-snoRNP complex; IEA:Compara. GO:0005732; C:small nucleolar ribonucleoprotein complex; IDA:RGD. GO:0008649; F:rRNA methyltransferase activity; NAS:RGD. GO:0030515; F:snoRNA binding; IEA:Compara. GO:0030519; F:snoRNP binding; TAS:UniProtKB. GO:0051082; F:unfolded protein binding; TAS:UniProtKB. GO:0006608; P:snRNP protein import into nucleus; IDA:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |