CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030648
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 BetaCstF-64 variant 2 
Protein Synonyms/Alias
  
Gene Name
 CSTF2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
145EQMFELMKQMKLCVQubiquitination[1, 2]
148FELMKQMKLCVQNSPubiquitination[2]
189VDPEIALKILHRQTNubiquitination[1, 2]
592ILKEQIQKSTGAP**ubiquitination[1]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 597 AA 
Protein Sequence
MAGLTVRDPA VDRSLRSVFV GNIPYEATEE QLKDIFSEVG PVVSFRLVYD RETGKPKGYG 60
FCEYQDQETA LSAMRNLNGR EFSGRALRVD NAASEKNKEE LKSLGTGAPV IESPYGETIS 120
PEDAPESISK AVASLPPEQM FELMKQMKLC VQNSPQEARN MLLQNPQLAY ALLQAQVVMR 180
IVDPEIALKI LHRQTNIPTL IAGNPQPVHG AGPGSGSNVS MNQQNPQAPQ AQSLGGMHVN 240
GAPPLMQASM QGGVPAPGQM PAAVTGPGPG SLAPGGGMQA QVGMPGSGPV SMERGQGTLQ 300
HSPVGPAGPA SIERVNVPMQ DPRAAMQRGS LPANVPTPRG LLGDAPNDPR GGTLLSVTGE 360
VEPRGYLGPP HQGPPMHHVP GHESRGPPPH ELRGGPLPEP RPLMAEPRGP MLDQRGPPLD 420
GRGGRDPRGI DARGMEARAM EARGLDARGL EARAMEARAM EARAMEARAM EARAMEVRGM 480
EARGMDTRGP VPGPRGPIPS GMQGPSPINM GAVVPQGSRQ VPVMQGTGMQ GASIQGGSQP 540
GGFSPGQNQV TPQDHEKAAL IMQVLQLTAD QIAMLPPEQR QSILILKEQI QKSTGAP 597 
Gene Ontology
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0000166; F:nucleotide binding; IEA:InterPro. 
Interpro
 IPR025742; CSTF2_hinge.
 IPR026896; CSTF_C.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
 PF14327; CSTF2_hinge
 PF14304; CSTF_C
 PF00076; RRM_1 
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS