UniProt Accession

 F8WA86_HUMAN; F8WA86 

Genbank Protein ID

 AC093429; AC105942 

Genbank Nucleotide ID

  

Protein Name

 Calponin-3 

Protein Synonyms/Alias

  

Gene Name

 CNN3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
6	**MTHFNKGPSYGLS	acetylation	[1, 2]
17	YGLSAEVKNKIASKY	ubiquitination	[3]
23	VKNKIASKYDHQAEE	acetylation	[1, 2]

Reference

 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 283 AA 

Protein Sequence

Gene Ontology

 GO:0031032; P:actomyosin structure organization; IEA:InterPro. 

Interpro

 IPR001997; Calponin.
 IPR000557; Calponin_repeat.
 IPR001715; CH-domain.
 IPR003096; SM22_calponin. 

Pfam

 PF00402; Calponin
 PF00307; CH 

SMART

 SM00033; CH 

PROSITE

 PS01052; CALPONIN_1
 PS51122; CALPONIN_2
 PS50021; CH 

PRINTS

 PR00889; CALPONIN.
 PR00888; SM22CALPONIN.