UniProt Accession

 GCSH_YEAST; P39726; D6VPH2 

Genbank Protein ID

 U12980; BK006935 

Genbank Nucleotide ID

 AAC04987.1; DAA06942.1 

Protein Name

 Glycine cleavage system H protein, mitochondrial 

Protein Synonyms/Alias

 Glycine decarboxylase complex subunit H 

Gene Name

 GCV3 

Gene Synonyms/Alias

 YAL044C; FUN40 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
32	GNALNKNKLPFLYSS	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 The glycine cleavage system (glycine decarboxylase complex) catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity). 

Sequence Annotation

 MOD_RES 102 102 N6-lipoyllysine (By similarity).  

Keyword

 Complete proteome; Lipoyl; Mitochondrion; Reference proteome; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 170 AA 

Protein Sequence

Gene Ontology

 GO:0005960; C:glycine cleavage complex; ISA:SGD.
 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0006546; P:glycine catabolic process; IMP:SGD.
 GO:0019464; P:glycine decarboxylation via glycine cleavage system; IEA:InterPro.
 GO:0006730; P:one-carbon metabolic process; IGI:SGD.
 GO:0009249; P:protein lipoylation; IMP:SGD. 

Interpro

 IPR003016; 2-oxoA_DH_lipoyl-BS.
 IPR002930; GCV_H.
 IPR017453; GCV_H_sub.
 IPR011053; Single_hybrid_motif. 

Pfam

 PF01597; GCV_H 

SMART

  

PROSITE

 PS00189; LIPOYL 

PRINTS