CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015987
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Filamin-A-interacting protein 1 
Protein Synonyms/Alias
 FILIP 
Gene Name
 FILIP1 
Gene Synonyms/Alias
 KIAA1275 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
444KLEEAFSKSKSECTQubiquitination[1]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
 By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A (By similarity). 
Sequence Annotation
  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1213 AA 
Protein Sequence
MRSRNQGGES ASDGHISCPK PSIIGNAGEK SLSEDAKKKK KSNRKEDDVM ASGTVKRHLK 60
TSGECERKTK KSLELSKEDL IQLLSIMEGE LQAREDVIHM LKTEKTKPEV LEAHYGSAEP 120
EKVLRVLHRD AILAQEKSIG EDVYEKPISE LDRLEEKQKE TYRRMLEQLL LAEKCHRRTV 180
YELENEKHKH TDYMNKSDDF TNLLEQERER LKKLLEQEKA YQARKEKENA KRLNKLRDEL 240
VKLKSFALML VDERQMHIEQ LGLQSQKVQD LTQKLREEEE KLKAITSKSK EDRQKLLKLE 300
VDFEHKASRF SQEHEEMNAK LANQESHNRQ LRLKLVGLTQ RIEELEETNK NLQKAEEELQ 360
ELRDKIAKGE CGNSSLMAEV ENLRKRVLEM EGKDEEITKT ESQCRELRKK LQEEEHHSKE 420
LRLEVEKLQK RMSELEKLEE AFSKSKSECT QLHLNLEKEK NLTKDLLNEL EVVKSRVKEL 480
ECSESRLEKA ELSLKDDLTK LKSFTVMLVD ERKNMMEKIK QEERKVDGLN KNFKVEQGKV 540
MDVTEKLIEE SKKLLKLKSE MEEKVYNLTR ERDELIGKLK SEEEKSSELS CSVDLLKKRL 600
DGIEEVEREI TRGRSRKGSE LTCPEDNKIK ELTLEIERLK KRLQQLEVVE GDLMKTEDEY 660
DQLEQKFRTE QDKANFLSQQ LEEIKHQIAK NKAIEKGEVV SQEAELRHRF RLEEAKSRDL 720
KAEVQALKEK IHELMNKEDQ LSQLQVDYSV LQQRFMEEEN KNKNMGQEVL NLTKELELSK 780
RYSRALRPSV NGRRMVDVPV TSTGVQTDAV SGEAAEEETP AVFIRKSFQE ENHIMSNLRQ 840
VGLKKPVERS SVLDRYPPAA NELTMRKSWI PWMRKRENGP SITQEKGPRT NSSPGHPGEV 900
VLSPKQGQPL HIRVTPDHEN STATLEITSP TSEEFFSSTT VIPTLGNQKP RITIIPSPNV 960
MPQKQKSGDT TLGPERAMSP VTITTFSREK TPESGRGAFA DRPTSPIQIM TVSTSAAPAE 1020
IAVSPESQEM PMGRTILKVT PEKQTVPTPV RKYNSNANII TTEDNKIHIH LGSQFKRSPG 1080
TSGEGVSPVI TVRPVNVTAE KEVSTGTVLR SPRNHLSSRP GASKVTSTIT ITPVTTSSAR 1140
GTQSVSGQDG SSQRPTPTRI PMSKGMKAGK PVVAAPGAGN LTKFEPRAET QSMKIELKKS 1200
AASSTTSLGG GKG 1213 
Gene Ontology
  
Interpro
 IPR019131; Cortactin-binding_p2_N. 
Pfam
 PF09727; CortBP2 
SMART
  
PROSITE
  
PRINTS