CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021689
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable cation-transporting ATPase 13A1 
Protein Synonyms/Alias
  
Gene Name
 ATP13A1 
Gene Synonyms/Alias
 ATP13A; KIAA1825; CGI-152 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
58VLSFEFQKIKYSYDAubiquitination[1]
69SYDALEKKQFLPVAFubiquitination[1]
121PDFSELFKERATAPFubiquitination[1]
190IQVYRSRKWRPIASDubiquitination[1]
307GFNTSQGKLLRTILFubiquitination[1]
437VAGLRDGKEVTPVSSubiquitination[1]
474LVGDPLEKAMLTAVDubiquitination[1]
832DESTPIVKLGDASIAubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
 ACT_SITE 533 533 4-aspartylphosphate intermediate (By
 METAL 864 864 Magnesium (By similarity).
 METAL 868 868 Magnesium (By similarity).
 MOD_RES 899 899 Phosphoserine.
 MOD_RES 935 935 Phosphoserine (By similarity).
 CARBOHYD 287 287 N-linked (GlcNAc...) (Potential).
 CARBOHYD 420 420 N-linked (GlcNAc...).  
Keyword
 Alternative splicing; ATP-binding; Complete proteome; Glycoprotein; Hydrolase; Magnesium; Membrane; Metal-binding; Nucleotide-binding; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1204 AA 
Protein Sequence
MEKWEELNSH QPGEEYDPSK ATFVKVVPTP NNGSTELVAL HRNEGEDGLE VLSFEFQKIK 60
YSYDALEKKQ FLPVAFPVGN AFSYYQSNRG FQEDSEIRAA EKKFGSNKAE MVVPDFSELF 120
KERATAPFFV FQVFCVGLWC LDEYWYYSVF TLSMLVAFEA SLVQQQMRNM SEIRKMGNKP 180
HMIQVYRSRK WRPIASDEIV PGDIVSIGRS PQENLVPCDV LLLRGRCIVD EAMLTGESVP 240
QMKEPIEDLS PDRVLDLQAD SRLHVIFGGT KVVQHIPPQK ATTGLKPVDS GCVAYVLRTG 300
FNTSQGKLLR TILFGVKRVT ANNLETFIFI LFLLVFAIAA AAYVWIEGTK DPSRNRYKLF 360
LECTLILTSV VPPELPIELS LAVNTSLIAL AKLYMYCTEP FRIPFAGKVE VCCFDKTGTL 420
TSDSLVVRGV AGLRDGKEVT PVSSIPVETH RALASCHSLM QLDDGTLVGD PLEKAMLTAV 480
DWTLTKDEKV FPRSIKTQGL KIHQRFHFAS ALKRMSVLAS YEKLGSTDLC YIAAVKGAPE 540
TLHSMFSQCP PDYHHIHTEI SREGARVLAL GYKELGHLTH QQAREVKREA LECSLKFVGF 600
IVVSCPLKAD SKAVIREIQN ASHRVVMITG DNPLTACHVA QELHFIEKAH TLILQPPSEK 660
GRQCEWRSID GSIVLPLARG SPKALALEYA LCLTGDGLAH LQATDPQQLL RLIPHVQVFA 720
RVAPKQKEFV ITSLKELGYV TLMCGDGTND VGALKHADVG VALLANAPER VVERRRRPRD 780
SPTLSNSGIR ATSRTAKQRS GLPPSEEQPT SQRDRLSQVL RDLEDESTPI VKLGDASIAA 840
PFTSKLSSIQ CICHVIKQGR CTLVTTLQMF KILALNALIL AYSQSVLYLE GVKFSDFQAT 900
LQGLLLAGCF LFISRSKPLK TLSRERPLPN IFNLYTILTV MLQFFVHFLS LVYLYREAQA 960
RSPEKQEQFV DLYKEFEPSL VNSTVYIMAM AMQMATFAIN YKGPPFMESL PENKPLVWSL 1020
AVSLLAIIGL LLGSSPDFNS QFGLVDIPVE FKLVIAQVLL LDFCLALLAD RVLQFFLGTP 1080
KLKVPS 1086 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0006200; P:ATP catabolic process; IEA:GOC. 
Interpro
 IPR006544; ATPase_P-typ_Cation_typ_V.
 IPR023299; ATPase_P-typ_cyto_domN.
 IPR018303; ATPase_P-typ_P_site.
 IPR008250; ATPase_P-typ_transduc_dom_A.
 IPR001757; Cation_transp_P_typ_ATPase.
 IPR023214; HAD-like_dom. 
Pfam
 PF00122; E1-E2_ATPase 
SMART
  
PROSITE
 PS00154; ATPASE_E1_E2 
PRINTS
 PR00119; CATATPASE.