CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026901
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ16308 fis, clone PUAEN2006335 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
528NRHVYEGKDGAIEDIacetylation[1]
540EDIITALKKNNITKFubiquitination[2]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 568 AA 
Protein Sequence
MGSEVVAGNS VGPTMGAASS GPLPPPPPPL PPSSDTPETV QNGPVTPPMP PPPPLPGPAA 60
ETVPAPPLAP PLPSAPPLPG TSSPTVVFNS GLAAVKIKKP IKTKFRMPVF NWVALKPNQI 120
NGTVFNEIDD ERILEDLNVD EFEEIFKTKA QGPAIDLSSS KQKIPQKGSN KVTLLEANRA 180
KNLAITLRKA GKTADEICKA IHVFDLKTLP VDFVECLMRF LPTENEVKVL RLYERERKPL 240
ENLSDEDRFM MQFSKIERLM QKMTIMAFIG NFAESIQMLT PQLHAIIAAS VSIKSSQKLK 300
KILEIILALG NYMNSSKRGA VYGFKLQSLD LLLDTKSTDR KQTLLHYISN VVKEKYHQVS 360
LFYNELHYVE KAAAVSLENV LLDVKELQRG MDLTKREYTM HDHNTLLKEF ILNNEGKLKK 420
LQDDAKIAQD AFDDVVKYFG ENPKTTPPSV FFPVFVRFVK AYKQAEEENE LRKKQEQALM 480
EKLLEQEALM EQQDPKSPSH KSKRQQQELI AELRRRQVKD NRHVYEGKDG AIEDIITALK 540
KNNITKFPNV HSRVRISSST PVVEDTQS 568 
Gene Ontology
 GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. 
Interpro
 IPR003104; Actin-bd_FH2/DRF_autoreg.
 IPR015425; FH2_actin-bd. 
Pfam
 PF02181; FH2 
SMART
 SM00498; FH2 
PROSITE
 PS51444; FH2 
PRINTS