UniProt Accession

 XNI_ECOLI; P38506; Q2MA36; Q46922 

Genbank Protein ID

 L07763; U29581; U00096; AP009048; M27177 

Genbank Nucleotide ID

 AAB40448.1; AAC75840.2; BAE76870.1 

Protein Name

 Protein Xni 

Protein Synonyms/Alias

 Exonuclease IX; ExoIX 

Gene Name

 ygdG 

Gene Synonyms/Alias

 exo; xni; b2798; JW5446 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
128	ATIVSTDKGYCQLLS	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 May have a role in processing of nucleic acids. It does not seem to be an exonuclease, as it can only bind 1 divalent metal cation, not the 2 that are thought to be necessary for exonuclease activity. 

Sequence Annotation

 METAL 9 9 Divalent metal cation (Potential).
 METAL 50 50 Divalent metal cation (Potential).
 METAL 102 102 Divalent metal cation (Potential).
 METAL 105 105 Divalent metal cation (Potential).
 METAL 127 127 Divalent metal cation (Potential).  

Keyword

 Coiled coil; Complete proteome; Metal-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 251 AA 

Protein Sequence

Gene Ontology

 GO:0008409; F:5'-3' exonuclease activity; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0008152; P:metabolic process; IEA:GOC. 

Interpro

 IPR020046; 5-3_exonucl_a-hlix_arch_N.
 IPR020045; 5-3_exonuclease_C.
 IPR002421; 5-3_exonuclease_N.
 IPR008918; HhH2.
 IPR022895; Uncharacterised_YgdG. 

Pfam

 PF01367; 5_3_exonuc
 PF02739; 5_3_exonuc_N 

SMART

 SM00475; 53EXOc
 SM00279; HhH2 

PROSITE

  

PRINTS