UniProt Accession

 CHEY_SALTY; P0A2D5; P06657 

Genbank Protein ID

 M12131; AE006468 

Genbank Nucleotide ID

 AAA27037.1; AAL20832.1 

Protein Name

 Chemotaxis protein CheY 

Protein Synonyms/Alias

  

Gene Name

 cheY 

Gene Synonyms/Alias

 STM1916 

Created Date

 July 27, 2013 

Organism

 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 

NCBI Taxa ID

 99287 

Lysine Modification

Position	Peptide	Type	References
26	RIVRNLLKELGFNNV	acetylation	[1]

Reference

 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 

Functional Description

 Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Shows autophosphatase activity which is enhanced by CheZ. 

Sequence Annotation

 DOMAIN 7 124 Response regulatory.
 METAL 12 12 Magnesium.
 METAL 13 13 Magnesium.
 METAL 57 57 Magnesium.
 METAL 59 59 Magnesium; via carbonyl oxygen.
 MOD_RES 57 57 4-aspartylphosphate.
 MOD_RES 92 92 N6-acetyllysine (By similarity).
 MOD_RES 109 109 N6-acetyllysine (By similarity).  

Keyword

 3D-structure; Acetylation; Chemotaxis; Complete proteome; Cytoplasm; Flagellar rotation; Magnesium; Metal-binding; Phosphoprotein; Reference proteome; Two-component regulatory system. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 129 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
 GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
 GO:0001539; P:ciliary or flagellar motility; IEA:UniProtKB-KW.
 GO:0035556; P:intracellular signal transduction; IEA:GOC.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 

Interpro

 IPR011006; CheY-like_superfamily.
 IPR001789; Sig_transdc_resp-reg_receiver. 

Pfam

 PF00072; Response_reg 

SMART

 SM00448; REC 

PROSITE

 PS50110; RESPONSE_REGULATORY 

PRINTS