UniProt Accession

 VTI1B_MOUSE; O88384 

Genbank Protein ID

 AF035208 

Genbank Nucleotide ID

 AAC23483.1 

Protein Name

 Vesicle transport through interaction with t-SNAREs homolog 1B 

Protein Synonyms/Alias

 Vesicle transport v-SNARE protein Vti1-like 1; Vti1-rp1 

Gene Name

 Vti1b 

Gene Synonyms/Alias

 Vti1l1 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
13	ASSEHFEKLHEIFRG	ubiquitination	[1]
190	NTNENLSKSRKILRS	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine (By similarity).  

Keyword

 3D-structure; Acetylation; Coiled coil; Complete proteome; Endosome; Lysosome; Membrane; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 232 AA 

Protein Sequence

Gene Ontology

 GO:0005794; C:Golgi apparatus; IDA:MGI.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0031902; C:late endosome membrane; ISS:UniProtKB.
 GO:0005765; C:lysosomal membrane; ISS:UniProtKB.
 GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; IEA:InterPro. 

Interpro

 IPR010989; t-SNARE.
 IPR000727; T_SNARE_dom.
 IPR007705; Vesicle_trsprt_v-SNARE_N. 

Pfam

 PF05008; V-SNARE 

SMART

 SM00397; t_SNARE 

PROSITE

  

PRINTS