CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014536
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Syntaxin-6 
Protein Synonyms/Alias
  
Gene Name
 Stx6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
16VVKGEVQKAVNTAQGubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
 Involved in intracellular vesicle trafficking. 
Sequence Annotation
 DOMAIN 163 225 t-SNARE coiled-coil homology.
 MOD_RES 2 2 N-acetylserine (By similarity).
 MOD_RES 2 2 Phosphoserine (By similarity).
 MOD_RES 152 152 Phosphoserine (By similarity).  
Keyword
 3D-structure; Acetylation; Coiled coil; Complete proteome; Golgi apparatus; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 255 AA 
Protein Sequence
MSMEDPFFVV KGEVQKAVNT AQGLFQRWTE LLQGPSAATR EEIDWTTNEL RNNLRSIEWD 60
LEDLDETISI VEANPRKFNL DATELSIRKA FITSTRQIVR DMKDQMSASS VQALAERKNR 120
QALLGDSSSQ NWDAGVTDRY GRLDRELQLA NSHFIEEQQA QQQLIVEQQD EQLELVSGSI 180
GVLKNMSQRI GGELEEQAVM LDDFSHELES TQSRLDNVMK KLAKVSHMTS DRRQWCAIAI 240
LFAVLLVVLT LFLVL 255 
Gene Ontology
 GO:0005769; C:early endosome; IEA:Compara.
 GO:0005794; C:Golgi apparatus; IDA:RGD.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IDA:RGD.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
 GO:0031201; C:SNARE complex; IEA:Compara.
 GO:0032588; C:trans-Golgi network membrane; IDA:BHF-UCL.
 GO:0007032; P:endosome organization; IEA:Compara.
 GO:0048193; P:Golgi vesicle transport; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0042147; P:retrograde transport, endosome to Golgi; IEA:Compara.
 GO:0006906; P:vesicle fusion; IEA:Compara.
 GO:0016192; P:vesicle-mediated transport; IDA:RGD. 
Interpro
 IPR015260; Syntaxin-6_N.
 IPR006012; Syntaxin/epimorphin_CS.
 IPR010989; t-SNARE.
 IPR000727; T_SNARE_dom. 
Pfam
 PF05739; SNARE
 PF09177; Syntaxin-6_N 
SMART
 SM00397; t_SNARE 
PROSITE
 PS00914; SYNTAXIN
 PS50192; T_SNARE 
PRINTS