CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044357
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 PWWP domain-containing protein MUM1 
Protein Synonyms/Alias
  
Gene Name
 MUM1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
6**MMADAKYVLCRWEubiquitination[1]
20EKRLWPAKVLARTATubiquitination[1]
123ADRSLRGKPMEHVSSubiquitination[1]
454GHMNPKMKGFTVSLKubiquitination[1]
471KHFDCKEKQTLLNQAubiquitination[1]
539TKLPQLSKGSPEEPVubiquitination[1]
582KLVEYIVKAKGAESHubiquitination[1]
643VYQEVGAKVLQRTNGubiquitination[1, 2]
686TAEEKYIKGPSLSYRubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 711 AA 
Protein Sequence
MMADAKYVLC RWEKRLWPAK VLARTATSTK NKRRKEYFLA VQILSLEEKI KVKSTEVEIL 60
EKSQIEAIAS SLASQNEVPA APLEELAYRR SLRVALDVLS EGSIWSQESS AGTGRADRSL 120
RGKPMEHVSS PCDSNSSSLP RGDVLGSSRP HRRRPCVQQS LSSSFTCEKD PECKVDHKKG 180
LRKSENPRGP LVLPAGGGAQ DESGSRIHHK NWTLASKRGG NSAQKASLCL NGSSLSEDDT 240
ERDMGSKGGS WAAPSLPSGV REDDPCANAE GHDPGLPLGS LTAPPAPEPS ACSEPGECPA 300
KKRPRLDGSQ RPPAVQLEPM AAGAAPSPGP GPGPRESVTP RSTARLGPPP SHASADATRC 360
LPCPDSQKLE KECQSSEESM GSNSMRSILE EDEEDEEPPR VLLYHEPRSF EVGMLVWHKH 420
KKYPFWPAVV KSVRQRDKKA SVLYIEGHMN PKMKGFTVSL KSLKHFDCKE KQTLLNQARE 480
DFNQDIGWCV SLITDYRVRL GCGSFAGSFL EYYAADISYP VRKSIQQDVL GTKLPQLSKG 540
SPEEPVVGCP LGQRQPCRKM LPDRSRAARD RANQKLVEYI VKAKGAESHL RAILKSRKPS 600
RWLQTFLSSS QYVTCVETYL EDEGQLDLVV KYLQGVYQEV GAKVLQRTNG DRIRFILDVL 660
LPEAIICAIS AVDEVDYKTA EEKYIKGPSL SYREKEIFDN QLLEERNRRR R 711 
Gene Ontology
  
Interpro
 IPR000313; PWWP. 
Pfam
 PF00855; PWWP 
SMART
  
PROSITE
  
PRINTS