CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-008082
UniProt Accession
HSP77_HUMAN
;
P48741
;
P19790
Genbank Protein ID
AL451067
;
M11236
Genbank Nucleotide ID
AAA52696.1
Protein Name
Putative heat shock 70 kDa protein 7
Protein Synonyms/Alias
Heat shock 70 kDa protein B
Gene Name
HSPA7
Gene Synonyms/Alias
HSP70B
Created Date
July 27, 2013
Organism
Homo sapiens (Human)
NCBI Taxa ID
9606
Lysine Modification
Position
Peptide
Type
References
321
STLEPVE
K
ALRDAKL
ubiquitination
[1]
Reference
[1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
Mol Cell. 2011 Oct 21;44(2):325-40. [
PMID: 21906983
]
Functional Description
Sequence Annotation
Keyword
ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome; Stress response.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
367 AA
Protein Sequence
MQAPRELAVG IDLGTTYSCV GVFQQGRVEI LANDQGNRTT PSYVAFTDTE RLVGDAAKSQ 60
AALNPHNTVF DAKRLIGRKF ADTTVQSDMK HWPFQVVSEG GKPKVRVCYR GEDKTFYPEE 120
ISSMVLSKMK ETAEAYLGQP VKHAVITVPT YFSNSQRQAT KDAGAIAGLK VLPIINEATA 180
AAIAYGLDRR GAGKRNVLIF DLGGGTFDVS VLSIDAGVFE VKATAGDTHL GGEDFDNRLV 240
NHFMEEFRRK HGKDLSGNKR ALRRLRTACE RAKRTPSSST QATLEIDSLF EGVDFYKSIT 300
RARFEELCSD LFRSTLEPVE KALRDAKLDK AQIHDFVLGG GLHSHPQGAE VAAGLLQRQG 360
AEQEHQP 367
Gene Ontology
GO:0005524
; F:ATP binding; NAS:UniProtKB.
GO:0006986
; P:response to unfolded protein; NAS:UniProtKB.
Interpro
IPR018181
; Heat_shock_70_CS.
IPR013126
; Hsp_70_fam.
Pfam
PF00012
; HSP70
SMART
PROSITE
PS00297
; HSP70_1
PS00329
; HSP70_2
PS01036
; HSP70_3
PRINTS
PR00301
; HEATSHOCK70.