CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029583
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Twf2 
Protein Synonyms/Alias
 Protein tyrosine kinase 9-like (A6-related protein) (Predicted), isoform CRA_b; Ptk9l protein 
Gene Name
 LOC684352 
Gene Synonyms/Alias
 Ptk9l; Ptk9l_predicted; Twf2; rCG_25118 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
14IHATEELKEFFAKARacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Kinase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 349 AA 
Protein Sequence
MAHQTGIHAT EELKEFFAKA RAGSIRLIKV IIEDEQLVLG ASQEPVGRWD QDYDRAVLPL 60
LDAQEPCYLL FRLDSQNAQG FEWLFLAWSP DNSPVRLKML YAATRATVKK EFGGGHIKDE 120
LFGTVKDDLS LAGYQKHLSS CAAPAPLTSA ERELQQIRIN EVKTEISVES KHQTLQGLAF 180
PLQPEAQRAL QQLKQKTVNY IQLKLDLERE TIELVHTEPT NVAQLPSRVP RDAARYHFFL 240
YKHTHEGDSL ESVVFIYSMP GYKCSIKERM LYSSCKSRLL DSVEQDFQLE IAKKIEIGDG 300
AELTAEFLYD EVHPKQHAFK QAFAKPKGPG GKRGHKRLIR GPGENGEDS 349 
Gene Ontology
 GO:0030175; C:filopodium; IEA:Compara.
 GO:0030426; C:growth cone; IEA:Compara.
 GO:0030027; C:lamellipodium; IEA:Compara.
 GO:0030016; C:myofibril; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
 GO:0032420; C:stereocilium; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:Compara.
 GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
 GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:Compara.
 GO:0051016; P:barbed-end actin filament capping; IEA:Compara.
 GO:0071363; P:cellular response to growth factor stimulus; IEA:Compara.
 GO:0071300; P:cellular response to retinoic acid; IEA:Compara.
 GO:0045773; P:positive regulation of axon extension; IEA:Compara.
 GO:0010592; P:positive regulation of lamellipodium assembly; IEA:Compara.
 GO:0010976; P:positive regulation of neuron projection development; IEA:Compara.
 GO:0042989; P:sequestering of actin monomers; IEA:Compara. 
Interpro
 IPR002108; Actin-bd_cofilin/tropomyosin. 
Pfam
 PF00241; Cofilin_ADF 
SMART
 SM00102; ADF 
PROSITE
 PS51263; ADF_H 
PRINTS