| Tag | Content |
|---|
| CPLM ID | CPLM-017832 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 445 |
Protein Synonyms/Alias | |
Gene Name | Znf445 |
Gene Synonyms/Alias | Zfp445 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 385 | NNDILELKHVKCVSV | ubiquitination | [1] | | 885 | EYGLHSDKPGLSYCQ | ubiquitination | [1] | | 904 | NIQELSGKLRKECDN | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 52 134 SCAN box.
DOMAIN 219 289 KRAB.
ZN_FING 470 492 C2H2-type 1.
ZN_FING 498 520 C2H2-type 2.
ZN_FING 553 575 C2H2-type 3.
ZN_FING 581 604 C2H2-type 4.
ZN_FING 634 656 C2H2-type 5.
ZN_FING 662 686 C2H2-type 6.
ZN_FING 718 740 C2H2-type 7.
ZN_FING 746 768 C2H2-type 8.
ZN_FING 796 818 C2H2-type 9.
ZN_FING 824 846 C2H2-type 10.
ZN_FING 933 955 C2H2-type 11.
ZN_FING 961 983 C2H2-type 12. |
Keyword | Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 986 AA |
Protein Sequence | MPPGRWHAAR SAQVSREQGC LRMVKEEEED GYISMQTARP QTLNRPGQEL FRQLFRQLRY 60
HESSGPLETL SRLQELCRWW MRPDVLSKAQ MLELLVLEQF LSILPGELRT WVQLHCPESG 120
AEVVALLEEL QRDLDGTPLK DPCLTQNPDV HWIGTSALQP AQIWSPASHL KNSSALEDHL 180
ETSHGIGICD VLAEQTDSPA VSVPDYFQLE EGIEYQEALT FQDVEVTFSQ EEWGCLNSAQ 240
RNLYRDVILE NYGNVVSVVG SSPKPALISW LEARKPWGVN ICTVQLKRDA DAAPEGGKLQ 300
IKPNKFILKQ KPSEYIEACV KTSVSPETSV SEETGLKESF KQKSRLQTSC GDSIQMKEMK 360
EGADISQRTG RESEVLRNND ILELKHVKCV SVSRKRLSFK HGYDRNFRKS SHHYNNKYGE 420
GLRGTGEGFG VYQNTGLKEN GKDRYGETSR KSWHAHPEHR QPSYSEEGLF QCRVCGKAFK 480
WRSNRIRHEK IHTGVKPYQC SLCEKAFQRL SSYRLHQKTH SKQKRGSSKY KNALTCSLDV 540
SHHLTDRDER KHLHCNQCGK NFSCKSYAIE HQRIHTQEKP YKCTRCRKTF RWKSNFSRHM 600
KLHHKEVYKQ EKRQEDFKQS YRQSQVISTV EKTFPCQNCG KTFTQKKSLI EHQRIHTGEK 660
PYQCSGCGET FTYRSSYIIH MKRTQHAIKI KPEHGCLTFS QGAVFPIPRG SHNTEGSNKC 720
KYCGKAFHNR SFLLIHERVH TREKPYQCRE CEKAFRWSSN LYRHQRKHFL HKRYKYRESK 780
ETSNLQSKIL IDQKPFWCQE CGKTFTRKRS LLDHKGIHSG ERRFKCNLCE KSFDRNYRLV 840
NHQRIHTTEQ PQWRDKDFVG IHARSVDQRK HSNTLQSEYG LHSDKPGLSY CQDVRLNIQE 900
LSGKLRKECD NPSDESSKSI AFQNVPTKKK ACHKCSTCGK TFKKHSHLIS HKRCHTKERP 960
FKCIVCGKTF RWSSNLTRHM KNHVRN 986 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0016032; P:viral reproduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |