CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018492
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Solute carrier family 15 member 4 
Protein Synonyms/Alias
 Peptide transporter 4; Peptide/histidine transporter 1 
Gene Name
 Slc15a4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
301HSLFDSCKMSRGGPFubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Proton oligopeptide cotransporter. Transports free histidine and certain di- and tripeptides (By similarity). 
Sequence Annotation
 MOD_RES 281 281 Phosphoserine.
 MOD_RES 292 292 Phosphoserine.
 MOD_RES 299 299 Phosphoserine.  
Keyword
 Complete proteome; Membrane; Peptide transport; Phosphoprotein; Protein transport; Reference proteome; Symport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 574 AA 
Protein Sequence
MEGERAPLLG SRRPAVSAAS AVFAGRRAAC GAVLLAELLE RAAFYGVTAN LVLFLNGAPF 60
DWEGAQASQA LLLFMGLTYL GSPFGGWLAD ARLGRARAIL LSLALYLLGL LAFPLLAAPR 120
SRSFLCGDPR PELVRNCSAP FPNGSASCPE NAARRCAPAT FAGLVLVGLG VATVKANITP 180
FGADQVKDRG PEATRRFFNW FYWSINLGAI LSLGGIAYIQ QNVSFFTGYL IPTVCVAIAF 240
LVFLCGQSVF ITKPPDGSAF TDMFRILTYS CCSQRGGQRR SGEGLGVFQQ SSKHSLFDSC 300
KMSRGGPFTE DKVEDVKALV KIVPVFLALI PYWTVYFQMQ TTYALQSLHL KIPEISSITT 360
THHTLPAAWL TMFDAVLILL LIPLKDKLVD PVLRRHGLLP SSLKRIAVGM FFVMCSAFAA 420
GILESKRLDL VKEKTINQTI GGVVYHAADL PIWWQIPQYV LIGISEIFAS IAGLEFAYSA 480
APKSMQSAIM GLFFFFSGIG SFVGSGLLAL VSLKAIGWMS SHTDFGNINS CHLHYYFFLL 540
AAIQGATLLL FLIVSVKYDR QRARTDGGPA STRT 574 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005290; F:L-histidine transmembrane transporter activity; IEA:Compara.
 GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
 GO:0006857; P:oligopeptide transport; IEA:InterPro.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR016196; MFS_dom_general_subst_transpt.
 IPR000109; POT_fam.
 IPR018456; PTR2_symporter_CS. 
Pfam
 PF00854; PTR2 
SMART
  
PROSITE
 PS01023; PTR2_2 
PRINTS