CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023967
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Kaptin 
Protein Synonyms/Alias
 Actin-associated protein 2E4 
Gene Name
 KPTN 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
47ELLAATLKGKVLGFRubiquitination[1]
49LAATLKGKVLGFRYQubiquitination[1]
88VSIDTFNKSPPKRGLubiquitination[1]
265LSAAKETKDRPLQDEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 May be involved in actin dynamics. May play a role in producing the sensory apparatus in hair cells. May play a role in actin rearrangements that accompany platelet activation and stereocilia formation. 
Sequence Annotation
  
Keyword
 Actin-binding; Cell projection; Complete proteome; Cytoplasm; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 436 AA 
Protein Sequence
MMGEAAVAAG PCPLREDSFT RFSSQSNVYG LAGGAGGRGE LLAATLKGKV LGFRYQDLRQ 60
KIRPVAKELQ FNYIPVDAEI VSIDTFNKSP PKRGLVVGIT FIKDSGDKGS PFLNIYCDYE 120
PGSEYNLDSI AQSCLNLELQ FTPFQLCHAE VQVGDQLETV FLLSGNDPAI HLYKENEGLH 180
QFEEQPVENL FPELTNLTSS VLWLDVHNFP GTSRRLSALG CQSGYVRVAH VDQRSREVLQ 240
MWSVLQDGPI SRVIVFSLSA AKETKDRPLQ DEYSVLVASM LEPAVVYRDL LNRGLEDQLL 300
LPGSDQFDSV LCSLVTDVDL DGRPEVLVAT YGQELLCYKY RGPESGLPEA QHGFHLLWQR 360
SFSSPLLAMA HVDLTGDGLQ ELAVVSLKGV HILQHSLIQA SELVLTRLRH QVEQRRRRLQ 420
GLEDGAGAGP AENAAS 436 
Gene Ontology
 GO:0015629; C:actin cytoskeleton; TAS:ProtInc.
 GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.
 GO:0005815; C:microtubule organizing center; TAS:ProtInc.
 GO:0005634; C:nucleus; TAS:ProtInc.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
 GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
 GO:0003779; F:actin binding; TAS:ProtInc.
 GO:0007015; P:actin filament organization; TAS:ProtInc.
 GO:0006928; P:cellular component movement; TAS:ProtInc.
 GO:0007605; P:sensory perception of sound; NAS:ProtInc. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS