CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005564
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphate acyltransferase 
Protein Synonyms/Alias
 Acyl-ACP phosphotransacylase; Acyl-[acyl-carrier-protein]--phosphate acyltransferase; Phosphate-acyl-ACP acyltransferase 
Gene Name
 plsX 
Gene Synonyms/Alias
 b1090; JW5156 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
95RVALELVKEGRAQACacetylation[1]
120GLAKLLLKPLEGIERacetylation[1]
191NIGEEEVKGLDSIRDacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Lipid biosynthesis; Lipid metabolism; Phospholipid biosynthesis; Phospholipid metabolism; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 356 AA 
Protein Sequence
MTRLTLALDV MGGDFGPSVT VPAALQALNS NSQLTLLLVG NSDAITPLLA KADFEQRSRL 60
QIIPAQSVIA SDARPSQAIR ASRGSSMRVA LELVKEGRAQ ACVSAGNTGA LMGLAKLLLK 120
PLEGIERPAL VTVLPHQQKG KTVVLDLGAN VDCDSTMLVQ FAIMGSVLAE EVVEIPNPRV 180
ALLNIGEEEV KGLDSIRDAS AVLKTIPSIN YIGYLEANEL LTGKTDVLVC DGFTGNVTLK 240
TMEGVVRMFL SLLKSQGEGK KRSWWLLLLK RWLQKSLTRR FSHLNPDQYN GACLLGLRGT 300
VIKSHGAANQ RAFAVAIEQA VQAVQRQVPQ RIAARLESVY PAGFELLDGG KSGTLR 356 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
 GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:EC.
 GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
 GO:0008654; P:phospholipid biosynthetic process; IGI:EcoCyc. 
Interpro
 IPR003664; FA_synthesis.
 IPR024084; IsoPropMal-DH-like_dom.
 IPR012281; Phospholipid_synth_PlsX-like. 
Pfam
 PF02504; FA_synthesis 
SMART
  
PROSITE
  
PRINTS